{"id":"W3027871354","doi":"10.1093/biolre/ioaa079","title":"Gene analysis of major signaling pathways regulated by gonadotropins in human ovarian granulosa tumor cells (KGN)†","year":2020,"lang":"en","type":"article","venue":"Biology of Reproduction","topic":"Kruppel-like factors research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Biology; Granulosa cell; Signal transduction; Protein kinase C; Folliculogenesis; Cell biology; Endocrinology; Ovarian follicle; Internal medicine; Luteinizing hormone; Forskolin; Cellular differentiation; Follicle-stimulating hormone; Follicular phase; Hormone; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003346517,0.0001451329,0.0003813875,0.0002114337,0.00003833809,0.000004105123,0.0002090605,0.0001872581,0.00006031936],"category_scores_gemma":[0.0001797379,0.0001450227,0.0001542036,0.0006920348,0.000199401,0.00000444454,0.00009528159,0.0001249361,0.000002714482],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002201715,"about_ca_system_score_gemma":0.00005549328,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003429824,"about_ca_topic_score_gemma":0.00002995211,"domain_scores_codex":[0.9982393,0.0002135631,0.0004622439,0.000737476,0.0001117424,0.0002356097],"domain_scores_gemma":[0.9990002,0.000009152892,0.0002404865,0.0005016726,0.000180484,0.00006799414],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001388751,0.00008782262,0.01446193,0.00003003355,0.0003250912,0.000001647345,0.00006530656,0.0002604578,0.9837571,0.00002434633,0.0002320903,0.0006153104],"study_design_scores_gemma":[0.000389711,0.0004615806,0.008498852,0.000004493872,0.00008066888,0.000001850493,0.00004451788,0.00009620547,0.9887583,0.00003405625,0.001502255,0.0001274932],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9973733,0.001167842,0.0006134941,0.0003313574,0.00007731358,0.000208527,0.0001884782,0.00001049759,0.00002915732],"genre_scores_gemma":[0.9979724,0.00008725954,0.0005239657,0.00002578413,0.0001365303,0.000007024549,0.00117968,0.00001554262,0.00005186757],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005963075,"threshold_uncertainty_score":0.5913853,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02025526124305501,"score_gpt":0.2661143764221013,"score_spread":0.2458591151790463,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}