{"id":"W3027911235","doi":"10.1016/j.mrgentox.2020.503199","title":"EURL ECVAM Genotoxicity and Carcinogenicity Database of Substances Eliciting Negative Results in the Ames Test: Construction of the Database","year":2020,"lang":"en","type":"review","venue":"Mutation Research/Genetic Toxicology and Environmental Mutagenesis","topic":"Carcinogens and Genotoxicity Assessment","field":"Biochemistry, Genetics and Molecular Biology","cited_by":37,"is_retracted":false,"has_abstract":true,"ca_institutions":"Health Canada","funders":"","keywords":"Ames test; Genotoxicity; Database; Carcinogen; Toxicology; Computational biology; Computer science; Chemistry; Biology; Genetics; Toxicity; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.006738805,0.001816725,0.002953182,0.02171381,0.0008901988,0.00278639,0.004395015,0.002181966,0.01141805],"category_scores_gemma":[0.0106579,0.0006864242,0.002506176,0.01520204,0.0006637141,0.002082962,0.002776104,0.001183733,0.009029674],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001615645,"about_ca_system_score_gemma":0.005385334,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.005437423,"about_ca_topic_score_gemma":0.004915814,"domain_scores_codex":[0.9921982,0.001290582,0.00196269,0.001037741,0.003190411,0.0003203068],"domain_scores_gemma":[0.9895611,0.002201295,0.002068111,0.001792016,0.003888889,0.0004886884],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.003665208,0.001358042,0.03488227,0.05749456,0.00130214,0.004382929,0.0008231283,0.01533137,0.153501,0.01691424,0.2547834,0.4555618],"study_design_scores_gemma":[0.0001309463,0.0004664188,0.02029501,0.00181536,0.0006077925,0.001336681,0.0001389108,0.001818214,0.03885783,0.002307308,0.9320944,0.0001311856],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"dataset","genre_gemma":"review","genre_scores_codex":[0.02228038,0.01414781,0.03688437,0.0004634814,0.0002085828,0.001643721,0.8973619,0.004333626,0.02267617],"genre_scores_gemma":[0.02330017,0.008177538,0.05170836,0.0005616422,0.00006253773,0.001760669,0.909891,0.0005274666,0.00401056],"genre_candidate":"review","genre_consensus":null,"teacher_disagreement_score":0.02171381,"threshold_uncertainty_score":0.03819716,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04371269448457069,"score_gpt":0.3307899434429596,"score_spread":0.2870772489583889,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}