{"id":"W3027938356","doi":"10.1016/j.jcyt.2020.03.492","title":"Safe and effective treatment of acute liver failure by allogeneic transplantation of stem cell-derived Encapsulated Liver Tissue without immunosuppression","year":2020,"lang":"en","type":"article","venue":"Cytotherapy","topic":"Liver physiology and pathology","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Montréal; Centre Hospitalier Universitaire Sainte-Justine","funders":"","keywords":"Immunosuppression; Bioartificial liver device; Cryopreservation; Stem cell; Liver transplantation; Induced pluripotent stem cell; Liver injury; In vivo; Transplantation; Immune system; Medicine; Immunology; Biology; Pharmacology; In vitro; Internal medicine; Hepatocyte; Cell biology; Biochemistry; Biotechnology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000148132,0.0002765109,0.0003189027,0.0002173234,0.0001341881,0.0002011635,0.0001450606,0.0001652256,0.0006143314],"category_scores_gemma":[0.0001253673,0.00004916757,0.0002323228,0.0001035728,0.0002845231,0.0001604623,0.0002032228,0.0004381694,0.0001250357],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007957711,"about_ca_system_score_gemma":0.0002579798,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007238633,"about_ca_topic_score_gemma":0.0001117662,"domain_scores_codex":[0.9999312,0.00001614904,0.00000575178,0.00000774799,0.00002325223,0.00001587229],"domain_scores_gemma":[0.9999532,0.0000106649,0.00001279465,0.000009643099,0.000004434745,0.000009408441],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.007548478,0.001579826,0.006930653,0.0006378554,0.0001291598,0.004160637,0.0001437799,0.002116288,0.6336082,0.005120195,0.001829576,0.3361952],"study_design_scores_gemma":[0.00391811,0.02540736,0.05348644,0.000340245,0.0007560808,0.03022428,0.0002157757,0.007316399,0.8150849,0.00563451,0.05753995,0.00007598722],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9235284,0.02881206,0.04070872,0.0006313536,0.0003890901,0.0001752141,0.0001370199,0.000236742,0.005381317],"genre_scores_gemma":[0.9904746,0.003990666,0.003904594,0.0001127183,0.0001736183,0.00006421471,0.000104997,0.00001949846,0.001155085],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006143314,"threshold_uncertainty_score":0.002055168,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01021479402207185,"score_gpt":0.2483866450472015,"score_spread":0.2381718510251297,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}