{"id":"W3028927304","doi":"10.1111/nyas.14371","title":"Alternatives to amyloid for Alzheimer's disease therapies—a symposium report","year":2020,"lang":"en","type":"article","venue":"Annals of the New York Academy of Sciences","topic":"Alzheimer's disease research and treatments","field":"Medicine","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"International Collaboration On Repair Discoveries; University of British Columbia; Artificial Intelligence in Medicine (Canada)","funders":"National Institute on Aging","keywords":"Amyloid (mycology); Alzheimer's disease; Disease; Medicine; Neuroscience; Amyloid β; Psychology; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002777305,0.001148114,0.0004463962,0.0007925943,0.001179325,0.004412886,0.0006663034,0.00314982,0.01145896],"category_scores_gemma":[0.001716294,0.0002989817,0.0007233701,0.0005199634,0.0006894955,0.003355953,0.001993745,0.005938839,0.004586179],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001323335,"about_ca_system_score_gemma":0.00260534,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007050669,"about_ca_topic_score_gemma":0.002595827,"domain_scores_codex":[0.9989561,0.0002053937,0.00005081854,0.0001169638,0.000510884,0.000159801],"domain_scores_gemma":[0.9989184,0.0001644558,0.00007843127,0.00002162662,0.0002962272,0.0005207529],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001062464,0.000134151,0.0000935401,0.0004654861,0.00001572866,0.000162001,0.0001579522,0.0000802153,0.001706456,0.006619404,0.9134077,0.07705106],"study_design_scores_gemma":[0.00001312977,0.000103311,0.0001622438,0.0002607678,0.00001097377,0.0001496938,0.0001273647,0.00003925529,0.0004029406,0.001671176,0.9970505,0.000008513494],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.003057534,0.4639565,0.0012301,0.2054849,0.2764314,0.0002060718,0.0003516701,0.0001404079,0.04914143],"genre_scores_gemma":[0.01910359,0.5614691,0.002853802,0.07771221,0.1862745,0.0002373687,0.0006144569,0.0001155958,0.1516194],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.01145896,"threshold_uncertainty_score":0.03833407,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1704943422079031,"score_gpt":0.4106259421904065,"score_spread":0.2401315999825034,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}