{"id":"W3029103020","doi":"10.1200/jco.2020.38.15_suppl.6577","title":"Nivolumab (Nivo) and ipilimumab (Ipi) in combination with radiotherapy (RT) in high-risk patients (pts) with locally advanced squamous cell carcinoma of the head and neck (LA SCCHN).","year":2020,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Cancer Immunotherapy and Biomarkers","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Bristol-Myers Squibb Canada","keywords":"Medicine; Nivolumab; Mucositis; Internal medicine; Ipilimumab; Oncology; Radiation therapy; Odynophagia; Chemotherapy; Gastroenterology; Cancer; Immunotherapy; Esophagus","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004668668,0.0003502808,0.0006410882,0.000190752,0.0002362155,0.0003886005,0.0003357023,0.0003196388,0.0009268833],"category_scores_gemma":[0.0004570327,0.0002323846,0.0004098197,0.0002512591,0.0002992649,0.0002948343,0.0002541603,0.0006386784,0.0002119965],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008142468,"about_ca_system_score_gemma":0.0008754411,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001324321,"about_ca_topic_score_gemma":0.004780457,"domain_scores_codex":[0.9998305,0.00006986387,0.00001298328,0.000030286,0.00001962892,0.00003663746],"domain_scores_gemma":[0.9998042,0.00004274924,0.00003896233,0.000007267145,0.000008452253,0.00009839581],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.3421049,0.0443459,0.2027621,0.001641849,0.001279705,0.001828745,0.00108414,0.0101765,0.07989722,0.0002855463,0.002679745,0.3119136],"study_design_scores_gemma":[0.04188855,0.6594111,0.2627896,0.000150734,0.001469301,0.001792388,0.0004651606,0.007846749,0.01590145,0.0002279312,0.00800355,0.00005355383],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9984044,0.0009347471,0.00006883476,0.00005678567,0.0000121062,0.0001065128,0.00005817707,0.000006675738,0.0003517543],"genre_scores_gemma":[0.9985681,0.0005801262,0.0002929951,0.00005881019,0.0000288974,0.0001023066,0.0001014875,0.000001766561,0.0002654394],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001324321,"threshold_uncertainty_score":0.005907774,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0202377699414593,"score_gpt":0.3239809890090967,"score_spread":0.3037432190676373,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}