{"id":"W3029622210","doi":"10.1200/jco.2020.38.15_suppl.tps5091","title":"A phase III randomized study of neoadjuvant chemotherapy (NAC) alone or in combination with nivolumab (NIVO) ± linrodostat mesylate, followed by adjuvant postsurgical NIVO ± linrodostat, in cisplatin-eligible muscle invasive bladder cancer (MIBC).","year":2020,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Bladder and Urothelial Cancer Treatments","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Bristol-Myers Squibb Canada","keywords":"Medicine; Bladder cancer; Cystectomy; Cisplatin; Internal medicine; Oncology; Chemotherapy; Nivolumab; Carboplatin; Cancer; Urology; Immunotherapy","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002042043,0.001676348,0.002928578,0.000344322,0.0004786373,0.001372677,0.001002713,0.001833959,0.00767813],"category_scores_gemma":[0.001905987,0.0008479087,0.001681444,0.0004237902,0.001329691,0.001218003,0.0005190154,0.004006475,0.001704916],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001095298,"about_ca_system_score_gemma":0.002184866,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001277487,"about_ca_topic_score_gemma":0.003279621,"domain_scores_codex":[0.9993581,0.0003136989,0.00003408826,0.0001482674,0.00004499276,0.0001008008],"domain_scores_gemma":[0.998541,0.0002742929,0.0002532646,0.000133821,0.0001128828,0.0006847295],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.968604,0.01790939,0.0005570194,0.0002894857,0.000534102,0.00002196744,0.00004187733,0.0002623468,0.002466516,0.00006766756,0.0005715302,0.008674171],"study_design_scores_gemma":[0.811022,0.1847,0.001684296,0.00003631253,0.0005149854,0.00003185082,0.00003807913,0.0003966915,0.0003450002,0.0002022328,0.001010778,0.00001774934],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9775648,0.004035744,0.0009998983,0.001041939,0.00153809,0.01058395,0.001361345,0.0001204939,0.002753749],"genre_scores_gemma":[0.970798,0.00330473,0.003007408,0.002208375,0.0007135926,0.01198587,0.001717824,0.00004693988,0.006217326],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00767813,"threshold_uncertainty_score":0.02568585,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07030212255951653,"score_gpt":0.4326583298084913,"score_spread":0.3623562072489748,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}