{"id":"W3029693493","doi":"10.1002/jgm.3234","title":"Evaluation of DNA methylation status of toll‐like receptors 2 and 4 promoters in Behcet's disease","year":2020,"lang":"en","type":"article","venue":"The Journal of Gene Medicine","topic":"Ocular Diseases and Behçet’s Syndrome","field":"Medicine","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Montreal Neurological Institute and Hospital","funders":"","keywords":"TLR2; Methylation; Promoter; TLR4; DNA methylation; CpG site; Peripheral blood mononuclear cell; Innate immune system; Bisulfite sequencing; Receptor; Immunology; Biology; Molecular biology; Pathogenesis; Immune system; Gene; Gene expression; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002080472,0.00009172646,0.0003923533,0.000137039,0.00001532026,0.000001445284,0.00006811251,0.00002835508,0.0002198333],"category_scores_gemma":[0.0009315856,0.00005280576,0.00006279322,0.0002448565,0.0001300774,0.0000655473,0.00001749325,0.000126659,4.160752e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006647725,"about_ca_system_score_gemma":0.0003022749,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003693947,"about_ca_topic_score_gemma":0.00000444116,"domain_scores_codex":[0.9978921,0.0002744392,0.0005838876,0.00008042009,0.001046301,0.0001228787],"domain_scores_gemma":[0.9986231,0.00006793802,0.0004540549,0.0001323332,0.0004160073,0.0003065241],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00929979,0.000946706,0.1419034,0.001406996,0.001076851,0.0001478007,0.0214314,0.001351211,0.5795369,0.0000257592,0.002508732,0.2403645],"study_design_scores_gemma":[0.0198286,0.007873621,0.9231448,0.001922728,0.01032525,0.0001760657,0.004804191,0.008581857,0.02131324,0.0007012042,0.001114857,0.0002135579],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9822769,0.01058874,0.0001378039,0.006441846,0.0001484401,0.0003356642,0.000004357697,0.000002363897,0.00006385502],"genre_scores_gemma":[0.9982838,0.001187012,0.0001717401,0.0001717016,0.0001542739,0.000001026494,0.00000850691,0.000009873066,0.00001209172],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7812414,"threshold_uncertainty_score":0.240702,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04968700712188146,"score_gpt":0.3214019070107706,"score_spread":0.2717148998888892,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}