{"id":"W3029704721","doi":"10.3760/cma.j.issn.1674-6554.2014.04.011","title":"Associations between brain-derived neurotrophic factor gene polymorphisms and cognitive disorder in depression","year":2014,"lang":"en","type":"article","venue":"Zhonghua xingwei yixue yu naokexue zazhi","topic":"14-3-3 protein interactions","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"rs6265; Brain-derived neurotrophic factor; Allele; Internal medicine; Montreal Cognitive Assessment; Depression (economics); Cognition; Medicine; Major depressive disorder; Neurotrophic factors; Allele frequency; Oncology; Endocrinology; Psychiatry; Gastroenterology; Psychology; Genetics; Gene; Cognitive impairment; Biology; Receptor","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002008328,0.000318096,0.0003433505,0.0001787699,0.000255863,0.00008625218,0.0002261355,0.0003166175,0.00004723021],"category_scores_gemma":[0.001259818,0.0003339931,0.0001144731,0.0001956586,0.0001277224,0.00002801627,0.0002546366,0.0003708382,0.0000409905],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003635543,"about_ca_system_score_gemma":0.00006173662,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002808322,"about_ca_topic_score_gemma":0.0002067735,"domain_scores_codex":[0.9979281,0.0002828294,0.0004133849,0.0006970484,0.0002160454,0.0004625475],"domain_scores_gemma":[0.9988406,0.0002501823,0.000235925,0.0003777982,0.0001261112,0.0001693961],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00005850407,0.0001107908,0.2967155,0.00001018246,0.0000994384,0.000006060019,0.0001795123,0.00002913335,0.6924469,0.00002404181,0.000245964,0.01007394],"study_design_scores_gemma":[0.00185926,0.0002819269,0.7715749,0.00007716504,0.00005874127,0.00001694873,0.00003666186,0.0001332125,0.2198186,0.0002001557,0.005400655,0.0005417669],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9909736,0.0005849106,0.006368786,0.000549807,0.0002332456,0.000491665,0.0002712281,0.00004686569,0.00047988],"genre_scores_gemma":[0.9972856,0.00004988297,0.0004311651,0.0006240495,0.0004820856,0.00008672648,0.0004571095,0.00007168637,0.0005116711],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4748594,"threshold_uncertainty_score":0.9999112,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01104784090132775,"score_gpt":0.2601046978417713,"score_spread":0.2490568569404435,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}