{"id":"W3029895260","doi":"10.1016/j.celrep.2020.107693","title":"MKRN2 Physically Interacts with GLE1 to Regulate mRNA Export and Zebrafish Retinal Development","year":2020,"lang":"en","type":"article","venue":"Cell Reports","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"University Health Network; University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; National Institutes of Health; National Health Research Institutes","keywords":"Zebrafish; RNA Helicase A; Cell biology; Gene knockdown; Nuclear pore; Biology; RNA-binding protein; SUMO protein; Nuclear transport; Ribonucleoprotein; Nuclear export signal; Ubiquitin; Ubiquitin ligase; DEAD box; Messenger RNA; Nucleoporin; Nucleolin; RNA; Helicase; Genetics; Cell nucleus; Cytoplasm; Gene; Nucleolus","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009504224,0.0003346868,0.000170797,0.0002058821,0.0001896239,0.000265047,0.0002178144,0.0002459646,0.001963506],"category_scores_gemma":[0.0001084232,0.0002339024,0.0002532438,0.0001010549,0.0002130384,0.0001716954,0.0003519048,0.0003147688,0.0006456757],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004607144,"about_ca_system_score_gemma":0.0002240672,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001205245,"about_ca_topic_score_gemma":0.005412454,"domain_scores_codex":[0.9998541,0.00001569062,0.000008756077,0.00003837285,0.00005717417,0.00002591857],"domain_scores_gemma":[0.9999329,0.000008902219,0.00002625351,0.00000683483,0.000006527728,0.00001861479],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001848041,0.000002208362,0.0002485344,0.0000122744,0.000002834338,0.00004495909,0.000005692004,0.00004112727,0.9992874,0.00004982558,0.00001615851,0.0002705065],"study_design_scores_gemma":[0.000007870906,0.00004850256,0.01844908,0.000005237397,0.00001455181,0.0004385947,0.00002348671,0.00208945,0.9761508,0.00004368997,0.002723057,0.0000056499],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9905757,0.001344883,0.004809791,0.000105165,0.0000125728,0.00001090545,0.0002834331,0.0001209661,0.002736633],"genre_scores_gemma":[0.9901491,0.0003927919,0.003092584,0.00008320581,0.000004015438,0.00001335986,0.0004919628,0.0000490336,0.005723887],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001963506,"threshold_uncertainty_score":0.006568551,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009435951302625145,"score_gpt":0.2307716895612655,"score_spread":0.2213357382586403,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}