{"id":"W3030036873","doi":"10.1097/01.aoa.0000661484.91078.58","title":"A Biased Coin Up-and-Down Sequential Allocation Trial to Determine the Optimum Programmed Intermittent Epidural Bolus Time Interval Between 5 mL Boluses of Bupivacaine 0.125% With Fentanyl 2 µg/mL","year":2020,"lang":"en","type":"article","venue":"Obstetric Anesthesia Digest","topic":"Anesthesia and Pain Management","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Mount Sinai Hospital","funders":"","keywords":"Medicine; Bupivacaine; Anesthesia; Bolus (digestion); Fentanyl; Motor block; Local anesthetic; Surgery","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005499608,0.0004976411,0.00101096,0.0002811354,0.0001459143,0.000104312,0.0004573364,0.0001497083,0.00009060466],"category_scores_gemma":[0.0005113859,0.0003326432,0.0002448306,0.001116107,0.0002775984,0.0001429783,0.0001138966,0.0003046937,0.00008018102],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001263847,"about_ca_system_score_gemma":0.0001530308,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001050002,"about_ca_topic_score_gemma":0.000004912695,"domain_scores_codex":[0.9968029,0.0003074309,0.0008866041,0.0006719456,0.0007580762,0.000573025],"domain_scores_gemma":[0.9976423,0.0006779242,0.0004106022,0.0005801765,0.0001921596,0.0004968573],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.1206412,0.003337636,0.5474611,0.002499649,0.00317797,0.005713185,0.01668046,0.0003648307,0.003908626,0.0006831141,0.01700104,0.2785312],"study_design_scores_gemma":[0.13666,0.04559336,0.5838542,0.002192019,0.006567442,0.002338236,0.005798234,0.01088931,0.006524119,0.00003404961,0.1963276,0.003221479],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.967292,0.0002105964,0.0007197709,0.02764972,0.00005632998,0.003726486,0.000004147126,0.000169006,0.0001719103],"genre_scores_gemma":[0.9929423,0.00002706962,0.0008296167,0.004278812,0.0004559891,0.0002054747,0.0001446919,0.00008334228,0.00103268],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2753097,"threshold_uncertainty_score":0.9999126,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04200890008054904,"score_gpt":0.2646570277950025,"score_spread":0.2226481277144535,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}