{"id":"W3030114120","doi":"10.7326/acpjc-2001-135-3-083","title":"Continuous infusion of amphotericin B deoxycholate reduced overall mortality, side effects, and nephrotoxicity more than did rapid infusion","year":2001,"lang":"en","type":"article","venue":"ACP Journal Club","topic":"Pharmaceutical studies and practices","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"","keywords":"Medicine; Nephrotoxicity; Amphotericin B deoxycholate; Amphotericin B; Continuous infusion; Internal medicine; Pharmacology; Toxicity; Antifungal","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001698798,0.0006229574,0.003352086,0.0005542828,0.0002115257,0.001089056,0.0004975632,0.00147169,0.01303748],"category_scores_gemma":[0.005736444,0.0003171167,0.001510593,0.0006355691,0.0005789136,0.0008893335,0.0004158506,0.001842384,0.0008880608],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003346475,"about_ca_system_score_gemma":0.000717922,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005410389,"about_ca_topic_score_gemma":0.000593876,"domain_scores_codex":[0.9991721,0.0003825738,0.0001439226,0.000116174,0.0001145165,0.00007085176],"domain_scores_gemma":[0.9970502,0.001590417,0.0007145401,0.0001529266,0.0001419796,0.0003498818],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.8723602,0.002973636,0.0007168677,0.01009905,0.002407539,0.00006191371,0.00007894039,0.000164846,0.00831138,0.0002572979,0.002092889,0.1004754],"study_design_scores_gemma":[0.7457368,0.2051393,0.02235238,0.003094476,0.006212093,0.0002132969,0.0001171315,0.0004804077,0.005642456,0.0006762632,0.01026259,0.00007292708],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.802908,0.1751159,0.001737931,0.003009878,0.002688035,0.003232127,0.003713623,0.0002451989,0.007349342],"genre_scores_gemma":[0.9461498,0.04145477,0.002248965,0.001092451,0.001183276,0.001025315,0.0008084254,0.00005765441,0.005979294],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01303748,"threshold_uncertainty_score":0.04361469,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03941421222053081,"score_gpt":0.3619862003477183,"score_spread":0.3225719881271875,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}