{"id":"W3030139823","doi":"10.3390/insects11060327","title":"RNA Interference Is Enhanced by Knockdown of Double-Stranded RNases in the Yellow Fever Mosquito Aedes aegypti","year":2020,"lang":"en","type":"article","venue":"Insects","topic":"Insect Resistance and Genetics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":42,"is_retracted":false,"has_abstract":true,"ca_institutions":"Fisheries and Oceans Canada; University of Manitoba","funders":"Medical Research Council; National Health and Medical Research Council; Natural Sciences and Engineering Research Council of Canada; Mitacs","keywords":"RNA interference; Biology; RNA silencing; Aedes aegypti; Gene knockdown; Midgut; RNA; Gene silencing; Aedes; Insect; Virology; Small interfering RNA; Mosquito control; Larva; Gene; Genetics; Botany; Immunology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002106011,0.0003513232,0.0002535308,0.0001629532,0.00009326387,0.0002267898,0.0001319105,0.000168026,0.0004414509],"category_scores_gemma":[0.0001114215,0.0001765282,0.0002436246,0.00008947263,0.0001855945,0.0001553449,0.0001237456,0.0004118098,0.0001720806],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003140979,"about_ca_system_score_gemma":0.0001493215,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000780617,"about_ca_topic_score_gemma":0.001040419,"domain_scores_codex":[0.999884,0.00001635506,0.00001719661,0.00003134235,0.00003160131,0.00001950115],"domain_scores_gemma":[0.99991,0.00001278798,0.00004529335,0.000007191095,0.00001057999,0.0000141512],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001459757,0.000005063112,0.00006735022,0.00001172008,0.000001583418,0.000009964768,0.000003664966,0.00002394871,0.9996089,0.00002197282,0.000008835378,0.0002223218],"study_design_scores_gemma":[0.00001272827,0.0002099876,0.005068622,0.000004363772,0.00001351322,0.00008562853,0.0000131698,0.001420598,0.9923437,0.0000200393,0.0008045372,0.000003098867],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9920672,0.0009856989,0.005036926,0.00008380679,0.00003110177,0.00004331442,0.0004111386,0.0001078416,0.001232904],"genre_scores_gemma":[0.9885762,0.001098776,0.007387972,0.000100557,0.000009955274,0.00006134855,0.0006188354,0.00003275778,0.002113564],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000780617,"threshold_uncertainty_score":0.002278984,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0198839740172687,"score_gpt":0.2529568592909683,"score_spread":0.2330728852736996,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}