{"id":"W3030152038","doi":"10.1186/s12711-020-00546-6","title":"Selection signatures in tropical cattle are enriched for promoter and coding regions and reveal missense mutations in the damage response gene HELB","year":2020,"lang":"en","type":"article","venue":"Genetics Selection Evolution","topic":"Genetic and phenotypic traits in livestock","field":"Biochemistry, Genetics and Molecular Biology","cited_by":51,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph","funders":"","keywords":"Biology; Genetics; Single-nucleotide polymorphism; Genome; Gene; Indel; Introgression; Coding region; Genotype","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001797839,0.0001240282,0.0001044143,0.00006837481,0.0001547302,0.00002626793,0.0000624938,0.0001481144,0.000001643713],"category_scores_gemma":[0.0002248043,0.0001168896,0.00002671751,0.0002369109,0.00006914615,0.00000552227,0.00002294098,0.0001509189,3.727068e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003139415,"about_ca_system_score_gemma":0.00006441588,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001486425,"about_ca_topic_score_gemma":0.0002828986,"domain_scores_codex":[0.9989458,0.0002533071,0.0001930667,0.000335273,0.00008404625,0.0001885425],"domain_scores_gemma":[0.9996604,0.00005877906,0.00006884026,0.00008411189,0.00007047992,0.00005735986],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.001032641,0.00009722052,0.02781784,0.00005187859,0.00002123613,7.449636e-7,0.00151185,0.007939265,0.9590559,0.0009037012,0.001225485,0.0003422406],"study_design_scores_gemma":[0.0010202,0.0007742172,0.9767061,0.00001086574,0.00003031682,0.0000370543,0.0004342677,0.005409645,0.01327406,0.001552358,0.0005743258,0.0001766096],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9367778,0.0006127966,0.06062615,0.001379605,0.00004709849,0.0005211798,0.00001353923,0.00001057405,0.00001126197],"genre_scores_gemma":[0.9894559,0.00004813043,0.009903907,0.000224113,0.0001779207,0.00007367427,0.00003082417,0.00001460796,0.00007086396],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.9488882,"threshold_uncertainty_score":0.4766618,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01604709151665696,"score_gpt":0.2511032547201394,"score_spread":0.2350561632034825,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}