{"id":"W3030378084","doi":"10.1007/s12192-020-01123-y","title":"The regulation of Akt and FoxO transcription factors during dehydration in the African clawed frog (Xenopus laevis)","year":2020,"lang":"en","type":"article","venue":"Cell Stress and Chaperones","topic":"FOXO transcription factor regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":false,"ca_institutions":"Carleton University; McGill University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"FOXO3; Xenopus; Protein kinase B; FOXO1; African clawed frog; Phosphorylation; Biology; Skeletal muscle; Transcription factor; Cell biology; Dehydration; Internal medicine; Endocrinology; Biochemistry; Gene; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001116911,0.0001916174,0.0001768739,0.0002655443,0.0003444107,0.0002950229,0.0001695636,0.0002285489,0.001692056],"category_scores_gemma":[0.00008326625,0.0001725831,0.0002209628,0.0001013299,0.0003639006,0.000448521,0.0002830353,0.0003621282,0.0001707171],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004232085,"about_ca_system_score_gemma":0.0001661775,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002234873,"about_ca_topic_score_gemma":0.004691447,"domain_scores_codex":[0.999944,0.000007499292,0.000003365981,0.00001849394,0.000006945017,0.00001977455],"domain_scores_gemma":[0.9999224,0.000006086467,0.00002853901,0.000006086078,0.00001208188,0.00002492181],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003302241,0.00001350847,0.001174559,0.00002746748,0.000006510786,0.00004674052,0.00004554297,0.00004779112,0.9971893,0.0002700132,0.00005294693,0.0007953072],"study_design_scores_gemma":[0.00009132383,0.0004257997,0.3143281,0.000027254,0.00006385112,0.0004906617,0.0005292103,0.002043446,0.6759638,0.000604903,0.005393266,0.00003854038],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9966977,0.001027212,0.0007607848,0.0001295122,0.00001936795,0.000007070606,0.0002464844,0.00002898409,0.001082918],"genre_scores_gemma":[0.9946926,0.0004568683,0.0007117345,0.00008476777,0.000009042541,0.00001667658,0.0002427411,0.0000183814,0.003767293],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002234873,"threshold_uncertainty_score":0.005660474,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0119815883487096,"score_gpt":0.198859198488509,"score_spread":0.1868776101397994,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}