{"id":"W3030494473","doi":"10.1200/jco.20.00158","title":"Clinical Practice Guideline for Systemic Antifungal Prophylaxis in Pediatric Patients With Cancer and Hematopoietic Stem-Cell Transplantation Recipients","year":2020,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Antifungal resistance and susceptibility","field":"Medicine","cited_by":142,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute for Clinical Evaluative Sciences; Pediatric Oncology Group; SickKids Foundation; University of Toronto; Hospital for Sick Children; Princess Margaret Cancer Centre","funders":"Medical Research Council; University of Exeter; Astellas Pharma; Wellcome Trust; National Institute for Health and Care Research; Gilead Sciences; Pediatric Oncology Group of Ontario; Pfizer","keywords":"Medicine; Posaconazole; Echinocandin; Voriconazole; Guideline; Intensive care medicine; Transplantation; Hematopoietic stem cell transplantation; Itraconazole; Immunosuppression; Cancer; Internal medicine; Antifungal; Fluconazole; Dermatology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.02171144,0.002257654,0.003908789,0.006584892,0.001657171,0.00365558,0.007069888,0.01091242,0.006151654],"category_scores_gemma":[0.0744177,0.001333235,0.007602558,0.004761317,0.00143371,0.003703612,0.003365218,0.008580239,0.004022771],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.009000706,"about_ca_system_score_gemma":0.03962552,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.02559406,"about_ca_topic_score_gemma":0.03315513,"domain_scores_codex":[0.969417,0.01310018,0.009758119,0.001410763,0.005429179,0.0008847301],"domain_scores_gemma":[0.931933,0.02069072,0.01075481,0.001222886,0.03287191,0.002526659],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002141036,0.0003010531,0.003657994,0.0825777,0.001502066,0.001082338,0.001453684,0.003693205,0.001526151,0.009346194,0.6138811,0.2807645],"study_design_scores_gemma":[0.001303278,0.0002718113,0.006434785,0.2985265,0.003784453,0.001329278,0.000634564,0.003342072,0.0008353518,0.01161555,0.6716503,0.0002719926],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"other","genre_scores_codex":[0.005077324,0.3292058,0.07404713,0.4569529,0.02141074,0.03172833,0.01618625,0.00179418,0.06359734],"genre_scores_gemma":[0.03648895,0.2580799,0.4882025,0.1409003,0.004920601,0.03568098,0.02112801,0.0002882627,0.01431045],"genre_candidate":"other","genre_consensus":null,"teacher_disagreement_score":0.02559406,"threshold_uncertainty_score":0.1148224,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07317244729589775,"score_gpt":0.4379039100557185,"score_spread":0.3647314627598208,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}