{"id":"W3030656570","doi":"10.1200/jco.2020.38.15_suppl.e12625","title":"Locoregional recurrence following pathologic complete response in patients with T1-3 N0 breast cancer treated with neoadjuvant chemotherapy, breast conserving surgery and whole breast radiation: Is a trial of omission of radiation warranted?","year":2020,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Breast Cancer Treatment Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Jewish General Hospital; McGill University Health Centre","funders":"","keywords":"Medicine; Breast cancer; Breast-conserving surgery; Radiation therapy; Chemotherapy; Internal medicine; Retrospective cohort study; Stage (stratigraphy); Oncology; Neoadjuvant therapy; Complete response; Cancer; Surgery; Mastectomy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001556655,0.0001124781,0.0004337624,0.0001939036,0.0002648058,0.0003257857,0.0003495279,0.0003818952,0.0005962254],"category_scores_gemma":[0.002494964,0.000136021,0.0004976314,0.0003896377,0.0003653048,0.0003402715,0.000246977,0.0003983169,0.0000942421],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007221413,"about_ca_system_score_gemma":0.0008757288,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00104126,"about_ca_topic_score_gemma":0.002821621,"domain_scores_codex":[0.9992626,0.0003782425,0.0000946997,0.0001025361,0.00008960287,0.00007229633],"domain_scores_gemma":[0.9980226,0.000683882,0.0008952006,0.00008489676,0.00006874991,0.000244751],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.01174719,0.0003435003,0.9710619,0.0001002664,0.0001319739,0.000230154,0.00007698232,0.0001890366,0.0006656726,0.00001962531,0.00024219,0.0151914],"study_design_scores_gemma":[0.0008528889,0.007246973,0.9890058,0.00004081104,0.0002553983,0.0007686394,0.0001087705,0.0004436086,0.0005751759,0.00004554637,0.0006476443,0.00000871105],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9988279,0.0007432812,0.00003718338,0.00008101854,0.000006631641,0.00002798743,0.0000764466,0.000001982849,0.0001975142],"genre_scores_gemma":[0.9994237,0.0001856856,0.000067215,0.00007798334,0.00001520382,0.00002620651,0.0001715476,7.774074e-7,0.00003156971],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001556655,"threshold_uncertainty_score":0.008232474,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0478831947817463,"score_gpt":0.3466333199059837,"score_spread":0.2987501251242374,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}