{"id":"W3030811423","doi":"10.1200/jco.2020.38.15_suppl.8536","title":"Pivotal DREAMM-2 study: Single-agent belantamab mafodotin (GSK2857916) in patients with relapsed/refractory multiple myeloma (RRMM) refractory to proteasome inhibitors (PIs), immunomodulatory agents, and refractory and/or intolerant to anti-CD38 monoclonal antibodies (mAbs).","year":2020,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Multiple Myeloma Research and Treatments","field":"Medicine","cited_by":27,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre","funders":"GlaxoSmithKline","keywords":"Medicine; Neutropenia; Refractory (planetary science); Internal medicine; Gastroenterology; Febrile neutropenia; Multiple myeloma; Surgery; Toxicity","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002651691,0.001215185,0.001794029,0.0002598921,0.0002500663,0.001041045,0.001006668,0.0009129207,0.003430393],"category_scores_gemma":[0.001155737,0.0005267429,0.001827036,0.0003135854,0.0005751991,0.001036134,0.000497127,0.002437949,0.001030392],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001182024,"about_ca_system_score_gemma":0.001164921,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008008934,"about_ca_topic_score_gemma":0.002947939,"domain_scores_codex":[0.999288,0.0003845614,0.00003812735,0.0001296182,0.00007793305,0.00008182437],"domain_scores_gemma":[0.9993764,0.0001064504,0.0001698729,0.00005687913,0.00005082529,0.0002396138],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.8120707,0.01329286,0.01035596,0.002405474,0.004435652,0.0003125443,0.000460735,0.002872568,0.02724403,0.0005188172,0.01083926,0.1151914],"study_design_scores_gemma":[0.775604,0.1869148,0.02030865,0.0001322905,0.001525965,0.0007584956,0.00009539953,0.001431833,0.002702448,0.0003789143,0.01009625,0.0000509399],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9735311,0.01181384,0.001077525,0.001436401,0.0003011494,0.002288139,0.004396453,0.0001475985,0.005007682],"genre_scores_gemma":[0.9803247,0.003910747,0.002176868,0.001626007,0.0002644227,0.001825409,0.005766101,0.00004950303,0.004056278],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003430393,"threshold_uncertainty_score":0.01402366,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09030549551261925,"score_gpt":0.384794551510006,"score_spread":0.2944890559973868,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}