{"id":"W3030934466","doi":"10.1093/ofid/ofy210.1995","title":"2342. Treatment Implications of Herpes Simplex Virus Central Nervous System Infection in Canadian Infants <90 Days Old: A Pediatric Investigators Collaborative Network on Infections in Canada (PICNIC) Study","year":2018,"lang":"en","type":"article","venue":"Open Forum Infectious Diseases","topic":"Herpesvirus Infections and Treatments","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"SickKids Foundation; University of Toronto; University of British Columbia; Hospital for Sick Children; McGill University; Children's Hospital of Eastern Ontario; University of Ottawa; University of Alberta; Université de Montréal; Centre Hospitalier Universitaire Sainte-Justine; Western University","funders":"","keywords":"Medicine; Encephalitis; Herpes simplex virus; Pleocytosis; Meningitis; Pediatrics; Enterovirus; Disease; Retrospective cohort study; Internal medicine; Virus; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006621308,0.0004039197,0.0004344861,0.0005295254,0.001796178,0.001051767,0.0009675618,0.0004713399,0.001977654],"category_scores_gemma":[0.002490606,0.0002432081,0.0009997673,0.001943871,0.0002555626,0.000324038,0.0005749391,0.000784491,0.0001933232],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.01401336,"about_ca_system_score_gemma":0.026299,"about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_topic_score_codex":0.9688608,"about_ca_topic_score_gemma":0.9813225,"domain_scores_codex":[0.9992297,0.00007200159,0.00005282162,0.00006478379,0.0002988313,0.0002818708],"domain_scores_gemma":[0.9986472,0.00006338507,0.0003473864,0.00003180124,0.0004351623,0.0004751695],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0003424294,0.0001147393,0.9898116,0.0001341061,0.0001245502,0.0001135414,0.0002032406,0.0000763408,0.00007691894,0.0000946527,0.0029541,0.005953785],"study_design_scores_gemma":[0.00005995378,0.000104087,0.9976992,0.000109918,0.0001118906,0.00005612544,0.0003983818,0.0001217492,0.00002269901,0.00001553847,0.001293242,0.000007096717],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9695991,0.003762551,0.00007812911,0.0009355459,0.000084864,0.0003371984,0.01676048,0.000007695843,0.008434445],"genre_scores_gemma":[0.9889047,0.002254882,0.0002246789,0.0004918758,0.0000595161,0.0001398278,0.006511966,0.000006245331,0.001406435],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03113919,"threshold_uncertainty_score":0.1016746,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01341706631373209,"score_gpt":0.2835391367193867,"score_spread":0.2701220704056546,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}