{"id":"W3030942202","doi":"10.1126/science.aay9189","title":"The human tumor microbiome is composed of tumor type–specific intracellular bacteria","year":2020,"lang":"en","type":"article","venue":"Science","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2390,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dalhousie University","funders":"H2020 European Research Council; Genentech; National Institutes of Health; Ministry of Science, Technology and Space; European Commission; Rising Tide Foundation; National Cancer Institute; Weizmann Institute of Science; Bristol-Myers Squibb; American Association for Cancer Research; AstraZeneca; Israel Cancer Research Fund; Israel Science Foundation; United States-Israel Binational Science Foundation; GlaxoSmithKline","keywords":"Bacteria; Microbiome; Intracellular; Intracellular parasite; Biology; Human microbiome; Computational biology; Microbiology; Cell biology; Bioinformatics; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002064823,0.0002278822,0.0004082201,0.0005659447,0.000435658,0.0006449552,0.00006216652,0.0001919897,0.0009790713],"category_scores_gemma":[0.0003774702,0.0001444272,0.0002168866,0.00079034,0.0002500914,0.0002508144,0.0005387402,0.0002453536,0.0003768352],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001278106,"about_ca_system_score_gemma":0.000279232,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001635939,"about_ca_topic_score_gemma":0.002164102,"domain_scores_codex":[0.9998096,0.00003986639,0.0000109583,0.00006154949,0.00004404982,0.0000339234],"domain_scores_gemma":[0.9998397,0.00002279379,0.00006055179,0.00001456391,0.00003209374,0.00003035483],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.000580151,0.0001110437,0.2892945,0.0005005738,0.0002199738,0.0003044229,0.0007973503,0.0004107489,0.6159511,0.0007501401,0.001402382,0.08967764],"study_design_scores_gemma":[0.00001730201,0.000538018,0.9164109,0.0002184236,0.0001702695,0.001921876,0.001497068,0.001003846,0.04944224,0.001768151,0.02696507,0.0000467789],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9779354,0.01023952,0.004953418,0.0003385519,0.00004422283,0.00004226119,0.003004142,0.00005711921,0.003385381],"genre_scores_gemma":[0.9871604,0.005062862,0.005024337,0.0002138977,0.00002493182,0.00003218562,0.001295215,0.00002138566,0.001164618],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001635939,"threshold_uncertainty_score":0.003275275,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01817082297600962,"score_gpt":0.2631403041519986,"score_spread":0.244969481175989,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}