{"id":"W3031115534","doi":"10.1016/j.ajpath.2020.05.015","title":"M2 Macrophages and Phenotypic Modulation of Intestinal Smooth Muscle Cells Characterize Inflammatory Stricture Formation in Rats","year":2020,"lang":"en","type":"article","venue":"American Journal Of Pathology","topic":"Immune cells in cancer","field":"Immunology and Microbiology","cited_by":22,"is_retracted":false,"has_abstract":false,"ca_institutions":"Queen's University","funders":"","keywords":"Pathogenesis; Biology; Growth factor; Transforming growth factor beta; Transforming growth factor; Phenotype; Inflammation; Fibrosis; Cytokine; CD163; Pathology; Immunology; Cancer research; Endocrinology; Receptor; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002292467,0.0005674184,0.0003980907,0.001227662,0.0003825458,0.0002495509,0.0002006295,0.0004323643,0.001458924],"category_scores_gemma":[0.0001900073,0.0004422729,0.00040487,0.0002788444,0.0005869774,0.0004852567,0.0003155936,0.0009937297,0.0003086151],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000283024,"about_ca_system_score_gemma":0.0002799135,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006489246,"about_ca_topic_score_gemma":0.001193253,"domain_scores_codex":[0.9997694,0.0000333406,0.00001538642,0.00004286344,0.00002955718,0.0001094937],"domain_scores_gemma":[0.9996666,0.00002252318,0.00009459309,0.00003453983,0.00002190007,0.0001597916],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.005907055,0.0009452166,0.004754996,0.00003644051,0.0000137777,0.0004274086,0.0001323406,0.0000639279,0.9853401,0.0001551404,0.00006124536,0.002162477],"study_design_scores_gemma":[0.0002563181,0.01115503,0.1323267,0.00001847808,0.0001010585,0.001339261,0.0008588193,0.001109874,0.8510445,0.0002489407,0.001501164,0.00003988384],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9991574,0.000179322,0.0002852429,0.00003163181,0.0000106948,0.00001668263,0.00007008909,0.00001368081,0.0002352526],"genre_scores_gemma":[0.997781,0.0002081004,0.0003774426,0.00004298565,0.00001385248,0.00003952927,0.000150072,0.000008017008,0.001379064],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001458924,"threshold_uncertainty_score":0.004880548,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009374223342289106,"score_gpt":0.2186499624703377,"score_spread":0.2092757391280486,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}