{"id":"W3031838166","doi":"10.3390/antibiotics9060283","title":"Iron Chelation in Murine Models of Systemic Inflammation Induced by Gram-Positive and Gram-Negative Toxins","year":2020,"lang":"en","type":"article","venue":"Antibiotics","topic":"Sepsis Diagnosis and Treatment","field":"Medicine","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dalhousie University","funders":"Dalhousie University","keywords":"Inflammation; Sepsis; Intravital microscopy; Lipopolysaccharide; Lipoteichoic acid; Peptidoglycan; Microbiology; Systemic inflammation; Immunology; Biology; In vivo; Chemistry; Staphylococcus aureus; Bacteria","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007268944,0.001200621,0.0008120094,0.001073866,0.0004772809,0.0003688948,0.0005523983,0.001173012,0.001189734],"category_scores_gemma":[0.0001968794,0.0003790563,0.0004893123,0.0004680973,0.0007521929,0.0004904472,0.0003422543,0.002054567,0.0003213814],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005314071,"about_ca_system_score_gemma":0.0005165245,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007189548,"about_ca_topic_score_gemma":0.001079944,"domain_scores_codex":[0.9994208,0.0001536555,0.00005077042,0.000109052,0.0001222464,0.0001435519],"domain_scores_gemma":[0.999639,0.00003502569,0.0001271956,0.00003649063,0.00003230207,0.0001299738],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.004339413,0.001932697,0.0002941346,0.0001837553,0.00002040768,0.0001714213,0.0001040151,0.0003389329,0.9894366,0.0002496998,0.0001886854,0.002740251],"study_design_scores_gemma":[0.000748495,0.0279495,0.003961076,0.00005507838,0.00008945314,0.0004564279,0.00008588091,0.002315648,0.9608673,0.0002017156,0.003242548,0.00002684974],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9860851,0.004671546,0.005121978,0.0005329172,0.0002374216,0.0004419107,0.0007329236,0.0002877254,0.001888406],"genre_scores_gemma":[0.9783275,0.00410218,0.008889873,0.0003533489,0.0001014274,0.0009235414,0.0009932519,0.00006578032,0.006243088],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001200621,"threshold_uncertainty_score":0.0039801,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05875996101869414,"score_gpt":0.2952947600295406,"score_spread":0.2365347990108465,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}