{"id":"W3031838166","doi":"10.3390/antibiotics9060283","title":"Iron Chelation in Murine Models of Systemic Inflammation Induced by Gram-Positive and Gram-Negative Toxins","year":2020,"lang":"en","type":"article","venue":"Antibiotics","topic":"Sepsis Diagnosis and Treatment","field":"Medicine","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dalhousie University","funders":"Dalhousie University","keywords":"Inflammation; Sepsis; Intravital microscopy; Lipopolysaccharide; Lipoteichoic acid; Peptidoglycan; Microbiology; Systemic inflammation; Immunology; Biology; In vivo; Chemistry; Staphylococcus aureus; Bacteria","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005946366,0.0001103808,0.0002652221,0.00005673448,0.000018846,0.000008258429,0.00002323538,0.00008896085,0.000003860137],"category_scores_gemma":[0.0000667693,0.00009702331,0.0000312538,0.000171576,0.00002756957,0.000100548,0.00002049901,0.00008930384,0.000003784816],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006270622,"about_ca_system_score_gemma":0.00002373546,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001915189,"about_ca_topic_score_gemma":0.00002075635,"domain_scores_codex":[0.9992762,0.00003471775,0.0002691772,0.0001754714,0.0001416913,0.000102699],"domain_scores_gemma":[0.9995792,0.00007599265,0.0001198152,0.00008725248,0.00006805771,0.00006971092],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003831763,0.0009076198,0.332423,0.001041437,0.0002990642,0.00005509829,0.01744234,0.0007985064,0.6303002,0.004292253,0.0002072641,0.01185002],"study_design_scores_gemma":[0.003777281,0.001179174,0.2454343,0.0008954773,0.0002216904,0.00001177842,0.00126214,0.02397556,0.7227489,0.0003071509,0.000004968703,0.0001816267],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.997481,0.0002043684,0.000203177,0.001251927,0.00002216408,0.000500018,0.0000203865,0.00001768525,0.0002992453],"genre_scores_gemma":[0.9990538,0.0003457417,0.0003255322,0.0001403414,0.00003188598,9.668339e-7,0.00008199135,0.00001229993,0.000007480978],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.09244867,"threshold_uncertainty_score":0.3956496,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05875996101869414,"score_gpt":0.2952947600295406,"score_spread":0.2365347990108465,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}