{"id":"W3031862323","doi":"10.1101/2020.05.26.111013","title":"PelX is a UDP- <i>N</i> -acetylglucosamine C4-epimerase involved in Pel polysaccharide-dependent biofilm formation","year":2020,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Bacterial biofilms and quorum sensing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary; Hospital for Sick Children; University of Toronto","funders":"International Microbiome Centre, University of Calgary; Canada Research Chairs; National Institutes of Health; Hospital for Sick Children; National Center for Research Resources; Canterbury Medical Research Foundation; Canadian Institutes of Health Research; Sick Kids Foundation; Natural Sciences and Engineering Research Council of Canada; Cystic Fibrosis Canada; Alberta Innovates; U.S. Department of Energy","keywords":"Biofilm; Operon; Gene cluster; Gene; Mutant; Pseudomonas aeruginosa; Biology; Chemistry; Biochemistry; Bacteria; Microbiology; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00004896543,0.0004371339,0.0002161492,0.0001869322,0.0001269063,0.0002696151,0.0001595907,0.0002572251,0.001403552],"category_scores_gemma":[0.0001024124,0.0001384735,0.0002589078,0.0001933554,0.000146507,0.0001829902,0.0001675962,0.0003247812,0.000379392],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002344311,"about_ca_system_score_gemma":0.0001272859,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001093714,"about_ca_topic_score_gemma":0.0004748083,"domain_scores_codex":[0.9999481,0.000005379455,0.000003024379,0.00001353783,0.00002204014,0.000007884237],"domain_scores_gemma":[0.999956,0.000006128785,0.00001395061,0.000003611761,0.00000723838,0.00001300779],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000554093,0.0000131581,0.00071485,0.00003371623,0.000006113521,0.0001648429,0.00001339617,0.0001421945,0.9974504,0.00009049165,0.00008059446,0.001234914],"study_design_scores_gemma":[0.0000171603,0.0001788421,0.03467714,0.00001211321,0.00001877454,0.001159509,0.00008320705,0.005318976,0.9515841,0.0001254042,0.00681103,0.00001367442],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9908528,0.001242226,0.005492861,0.0001261332,0.0000314415,0.00002490603,0.0008950501,0.000172633,0.001162107],"genre_scores_gemma":[0.9850644,0.0006972829,0.005971382,0.00005291272,0.00001297899,0.00001492143,0.003602298,0.00002846182,0.004555204],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001403552,"threshold_uncertainty_score":0.004695296,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01496052195377255,"score_gpt":0.2181886562543947,"score_spread":0.2032281343006221,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}