{"id":"W3032046986","doi":"10.1056/nejmoa2004325","title":"Oral Relugolix for Androgen-Deprivation Therapy in Advanced Prostate Cancer","year":2020,"lang":"en","type":"article","venue":"New England Journal of Medicine","topic":"Prostate Cancer Treatment and Research","field":"Medicine","cited_by":436,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"Myovant Sciences","keywords":"Prostate cancer; Androgen deprivation therapy; Testosterone (patch); Medicine; Luteinizing hormone; Internal medicine; Androgen; Hormone antagonist; Hormone; Endocrinology; Gonadotropin-releasing hormone; Leuprorelin; Antagonist; Oncology; Cancer; Endocrine system; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006608202,0.0004059219,0.001029136,0.0002585018,0.0001598729,0.0002236962,0.0002552871,0.0002702621,0.002453322],"category_scores_gemma":[0.0004780265,0.0001335133,0.0005432884,0.0002251414,0.0003402486,0.0001477336,0.0001834276,0.0007615072,0.0002357678],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003058232,"about_ca_system_score_gemma":0.0006023754,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005014983,"about_ca_topic_score_gemma":0.001278932,"domain_scores_codex":[0.9997532,0.0001188403,0.00001845268,0.00002943246,0.00004869935,0.00003130927],"domain_scores_gemma":[0.9996729,0.0001058261,0.00008850065,0.00001327459,0.00001073467,0.0001087313],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.4975245,0.01211583,0.02468775,0.004043616,0.001892702,0.0005168599,0.0001730237,0.003235796,0.02667737,0.0004396281,0.003355511,0.4253375],"study_design_scores_gemma":[0.3168802,0.5810992,0.08106349,0.0003012834,0.001201974,0.002150577,0.00008501027,0.002250856,0.005250762,0.0004931947,0.009176414,0.00004707329],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9832628,0.01423483,0.0002854797,0.0002534358,0.00009397598,0.000523128,0.0001794012,0.00004352379,0.00112349],"genre_scores_gemma":[0.9938451,0.004375857,0.0004427145,0.0002229975,0.000133241,0.0002614281,0.0002470639,0.000005315887,0.0004663522],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002453322,"threshold_uncertainty_score":0.008207202,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05957229224554349,"score_gpt":0.3705046643917067,"score_spread":0.3109323721461631,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}