{"id":"W3032224644","doi":"10.1186/s12864-020-06789-3","title":"Distinctions between sex and time in patterns of DNA methylation across puberty","year":2020,"lang":"en","type":"article","venue":"BMC Genomics","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":26,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Children's Hospital; University of British Columbia","funders":"National Institute of Mental Health; Jacobs Foundation","keywords":"dNaM; Biology; DNA methylation; Testosterone (patch); Androgen; Physiology; Endocrinology; Internal medicine; Genetics; Hormone; Medicine; Gene; Gene expression","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001437748,0.00007444675,0.0001145603,0.00001401816,0.00002913201,0.00001160669,0.00005978014,0.00008937308,0.000006229018],"category_scores_gemma":[0.00006593053,0.00007852606,0.00003221272,0.00004754029,0.00002177712,0.000002455943,0.00008205853,0.00004182429,0.000002876457],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000008525195,"about_ca_system_score_gemma":0.00002519088,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002746306,"about_ca_topic_score_gemma":0.00009292327,"domain_scores_codex":[0.9994153,0.00004273088,0.0001979563,0.0001905518,0.00004676108,0.0001066831],"domain_scores_gemma":[0.9997132,0.00002201023,0.00006854182,0.0001153722,0.00002500223,0.00005584899],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001398839,0.000009909048,0.3910967,0.000019341,0.000008234379,1.153329e-7,0.0002739748,0.0002378812,0.6034766,0.00000674881,0.00000620689,0.004850306],"study_design_scores_gemma":[0.0004526519,0.0001459212,0.4156637,0.000003549424,0.00001420244,2.447472e-7,0.0001087856,0.0008868121,0.5784941,0.0001488539,0.003942849,0.0001383571],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9858963,0.0003178985,0.01334779,0.00007206503,0.00001741659,0.0001095621,0.0001090411,0.000003810988,0.000126115],"genre_scores_gemma":[0.9985235,0.00008748595,0.0009455289,0.00002514544,0.0001259339,0.000003897715,0.000200692,0.00001195366,0.00007587091],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02498253,"threshold_uncertainty_score":0.32022,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02590809982697432,"score_gpt":0.2703766437305222,"score_spread":0.2444685439035479,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}