{"id":"W3032298262","doi":"10.1371/journal.pone.0233859","title":"Effects of Biotin on survival, ensheathment, and ATP production by oligodendrocyte lineage cells in vitro","year":2020,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Biotin and Related Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Montreal Neurological Institute and Hospital","funders":"MedDay Pharmaceuticals; McGill University","keywords":"Biotin; Oligodendrocyte; Biology; Biotin deficiency; Viability assay; Cell biology; Myelin; In vitro; Biochemistry; Endocrinology; Central nervous system","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00004812501,0.00009766617,0.0001673422,0.00001773379,0.00002355888,0.000003869327,0.00004349033,0.0001104648,9.867853e-7],"category_scores_gemma":[0.00005844192,0.00008655804,0.00002332245,0.00006547776,0.00005023637,0.000001195494,0.00005291412,0.00009851149,0.000003444205],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00000462264,"about_ca_system_score_gemma":0.000006133553,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000008501706,"about_ca_topic_score_gemma":0.000001335727,"domain_scores_codex":[0.9993886,0.00003920159,0.0001215686,0.0002499766,0.0000863745,0.0001143067],"domain_scores_gemma":[0.9997964,0.00001240235,0.000044279,0.00008431356,0.0000204476,0.00004214018],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001818793,0.0004403016,0.0002518942,0.0002264808,0.0001393203,0.000001596441,0.0001317962,0.000001773549,0.9979383,0.000001135181,0.0005947101,0.0000907731],"study_design_scores_gemma":[0.0004755892,0.0003775356,0.0002464204,0.00006034453,0.00004590019,2.189324e-7,0.00002829179,0.00002675042,0.9982122,3.02106e-7,0.0004371848,0.00008924266],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.996438,0.002533365,0.000007186308,0.0005460063,0.00005021292,0.000223487,0.00001600827,0.000008664336,0.000177036],"genre_scores_gemma":[0.9949673,0.004281445,0.0002151913,0.0001657786,0.0001139109,0.000005815759,0.00002731075,0.00001159857,0.0002116125],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001748081,"threshold_uncertainty_score":0.3529734,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01420163723011275,"score_gpt":0.2012498933148255,"score_spread":0.1870482560847127,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}