{"id":"W3032298262","doi":"10.1371/journal.pone.0233859","title":"Effects of Biotin on survival, ensheathment, and ATP production by oligodendrocyte lineage cells in vitro","year":2020,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Biotin and Related Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Montreal Neurological Institute and Hospital","funders":"MedDay Pharmaceuticals; McGill University","keywords":"Biotin; Oligodendrocyte; Biology; Biotin deficiency; Viability assay; Cell biology; Myelin; In vitro; Biochemistry; Endocrinology; Central nervous system","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001869848,0.0002872265,0.0002588163,0.0001358581,0.0001682507,0.0002240722,0.0001758366,0.0002456693,0.001325472],"category_scores_gemma":[0.0001505988,0.0001019584,0.0001667265,0.0001399152,0.0001554569,0.0001630998,0.0002511104,0.0003249881,0.0002351508],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001853416,"about_ca_system_score_gemma":0.0002151539,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001772432,"about_ca_topic_score_gemma":0.003501724,"domain_scores_codex":[0.9998293,0.00004628401,0.0000219705,0.00003119776,0.00003907158,0.00003219911],"domain_scores_gemma":[0.9997991,0.00008177633,0.00003450069,0.00002033356,0.00002978082,0.00003459023],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003904548,0.00005132459,0.0001702339,0.00007962472,0.000005729246,0.00005467284,0.00004936266,0.0000671619,0.9979334,0.00004005997,0.00003131278,0.001126753],"study_design_scores_gemma":[0.00001237645,0.0006633097,0.002037213,0.000007282919,0.0000102627,0.00006421723,0.00003795402,0.0003195865,0.9957986,0.00002024932,0.001025998,0.000003041418],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.99257,0.003008184,0.001822623,0.00008362533,0.00004015442,0.00002365519,0.0004755732,0.00003665881,0.001939579],"genre_scores_gemma":[0.9926378,0.001585411,0.002344665,0.00003553672,0.000009484754,0.00003079209,0.0005101303,0.00001372272,0.002832462],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001772432,"threshold_uncertainty_score":0.004434109,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01420163723011275,"score_gpt":0.2012498933148255,"score_spread":0.1870482560847127,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}