{"id":"W3032335069","doi":"10.1200/jco.2020.38.15_suppl.7513","title":"Escalated dosing schedules of CC-486 for patients experiencing first acute myeloid leukemia (AML) relapse: Results from the phase III QUAZAR AML-001 maintenance trial.","year":2020,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Acute Myeloid Leukemia Research","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; University of Alberta Hospital; Alberta Hospital Edmonton","funders":"","keywords":"Medicine; Dosing; Internal medicine; Maintenance therapy; Neutropenia; Minimal residual disease; Febrile neutropenia; Surgery; Oncology; Chemotherapy; Bone marrow; Gastroenterology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001317223,0.0004155019,0.0009585978,0.0004086812,0.0001268606,0.0005101461,0.0005302191,0.0005302719,0.00284906],"category_scores_gemma":[0.001131134,0.0001657115,0.00117761,0.0004899447,0.0002474456,0.0003885129,0.0002272963,0.0008648324,0.0003647777],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009165932,"about_ca_system_score_gemma":0.0007332024,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001101395,"about_ca_topic_score_gemma":0.003292282,"domain_scores_codex":[0.9996864,0.0001444136,0.00003807143,0.00004655148,0.00004280874,0.00004190946],"domain_scores_gemma":[0.9993727,0.0001363969,0.0003131917,0.00002856761,0.00003456583,0.0001146503],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.5234577,0.005719827,0.01006559,0.006387896,0.005265872,0.0001909994,0.0002068288,0.002578821,0.0191803,0.0003964539,0.007582147,0.4189675],"study_design_scores_gemma":[0.6729273,0.2404663,0.05375113,0.0007442919,0.008015958,0.0007203152,0.0001237974,0.001494873,0.002897797,0.0004886999,0.01831503,0.0000544725],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9346584,0.05231801,0.0006951075,0.001320696,0.000176497,0.002195729,0.004717427,0.0001175028,0.003800689],"genre_scores_gemma":[0.9645595,0.0228609,0.001310362,0.001726272,0.0002225552,0.001451654,0.005924308,0.00002731276,0.00191697],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00284906,"threshold_uncertainty_score":0.009531081,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1112841023447469,"score_gpt":0.4399239634443466,"score_spread":0.3286398610995998,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}