{"id":"W3032786081","doi":"10.1016/j.ibmb.2020.103406","title":"CRISPR/Cas9-induced vitellogenin knockout lead to incomplete embryonic development in Plutella xylostella","year":2020,"lang":"en","type":"article","venue":"Insect Biochemistry and Molecular Biology","topic":"Insect Resistance and Genetics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":28,"is_retracted":false,"has_abstract":false,"ca_institutions":"Brock University","funders":"Fujian Agriculture and Forestry University; Natural Science Foundation of Fujian Province; National Natural Science Foundation of China","keywords":"Biology; Vitellogenin; Diamondback moth; Plutella; Yolk; Mutant; Insect; Embryogenesis; CRISPR; Vitellogenesis; Gene; Genetics; Embryo; Botany; Larva; Oocyte","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001352721,0.0004320113,0.0002973611,0.0003690928,0.0002982424,0.0004742979,0.0004161798,0.00050169,0.002606538],"category_scores_gemma":[0.0001066005,0.00032999,0.0004141633,0.0002137717,0.0003676178,0.0002424366,0.0004880183,0.001197463,0.001139786],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005907796,"about_ca_system_score_gemma":0.0003536105,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002704886,"about_ca_topic_score_gemma":0.003607337,"domain_scores_codex":[0.9998521,0.00001544977,0.00001601954,0.00003982943,0.00004360596,0.00003302114],"domain_scores_gemma":[0.9998276,0.00003633076,0.00005717179,0.00002262688,0.00001103113,0.0000451202],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000030025,0.000004384776,0.00007193879,0.00001630074,0.000003172357,0.00008225929,0.00001446621,0.00005353536,0.9993125,0.0001232353,0.00002973132,0.0002584399],"study_design_scores_gemma":[0.00003160627,0.00005121464,0.01373013,0.00001465254,0.00003560366,0.0005009423,0.00008702238,0.00182962,0.9777457,0.0001418124,0.005814783,0.00001703987],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9856302,0.001015529,0.00690976,0.0001653408,0.00007222806,0.00003095389,0.00216049,0.000443613,0.003571917],"genre_scores_gemma":[0.9818757,0.0003916206,0.001287926,0.00008099937,0.00000618003,0.00003192149,0.001473222,0.0001971278,0.01465521],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002704886,"threshold_uncertainty_score":0.008719742,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01932304054750137,"score_gpt":0.2678652490792644,"score_spread":0.248542208531763,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}