{"id":"W3032786081","doi":"10.1016/j.ibmb.2020.103406","title":"CRISPR/Cas9-induced vitellogenin knockout lead to incomplete embryonic development in Plutella xylostella","year":2020,"lang":"en","type":"article","venue":"Insect Biochemistry and Molecular Biology","topic":"Insect Resistance and Genetics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":28,"is_retracted":false,"has_abstract":false,"ca_institutions":"Brock University","funders":"Fujian Agriculture and Forestry University; Natural Science Foundation of Fujian Province; National Natural Science Foundation of China","keywords":"Biology; Vitellogenin; Diamondback moth; Plutella; Yolk; Mutant; Insect; Embryogenesis; CRISPR; Vitellogenesis; Gene; Genetics; Embryo; Botany; Larva; Oocyte","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001652033,0.0004266551,0.0003841772,0.0000795309,0.0001016138,0.00003296926,0.0003900023,0.0005188729,0.00001626472],"category_scores_gemma":[0.0001680992,0.0004521402,0.0001087537,0.0002744047,0.0001160954,0.000002832281,0.0003989624,0.0002546906,0.00003209219],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003767762,"about_ca_system_score_gemma":0.0002469231,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002128775,"about_ca_topic_score_gemma":0.00007855923,"domain_scores_codex":[0.9977017,0.0001118852,0.000431143,0.001001559,0.0001281716,0.000625536],"domain_scores_gemma":[0.9990534,0.00001823002,0.00009890529,0.000423512,0.00008689438,0.0003190895],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002845656,0.00004685564,0.001107377,0.00007541299,0.00006674739,0.0000599391,0.0001991204,0.0000207268,0.9940918,0.00002977677,0.0002504449,0.003767221],"study_design_scores_gemma":[0.0007701564,0.0004917678,0.0003087361,0.00002572096,0.00001458921,0.00004557722,0.00006768317,0.00001825833,0.9803663,0.0000339296,0.01729991,0.0005573199],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9935712,0.002393087,0.001946926,0.0009111722,0.00009185299,0.0003260989,0.00002554627,0.00002601332,0.0007081408],"genre_scores_gemma":[0.9920645,0.0001392917,0.002485288,0.004665592,0.0002014033,0.0000481816,0.0002081447,0.00004549088,0.0001421591],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01704947,"threshold_uncertainty_score":0.9997931,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01932304054750137,"score_gpt":0.2678652490792644,"score_spread":0.248542208531763,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}