{"id":"W3032974261","doi":"10.1111/bcp.14414","title":"Population pharmacokinetics of olanzapine in children","year":2020,"lang":"en","type":"article","venue":"British Journal of Clinical Pharmacology","topic":"Pharmaceutical studies and practices","field":"Medicine","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre Hospitalier Universitaire Sainte-Justine","funders":"Duke Clinical Research Institute; National Center for Advancing Translational Sciences; National Institute of Child Health and Human Development; Hospital for Sick Children; University of Louisville; University of North Carolina at Chapel Hill; Wichita Medical Research and Education Foundation; Eunice Kennedy Shriver National Institute of Child Health and Human Development; Children's Hospital of Philadelphia","keywords":"NONMEM; Olanzapine; Dosing; Medicine; Pharmacokinetics; Population; Volume of distribution; Pediatrics; Population pharmacokinetics; Internal medicine; Schizophrenia (object-oriented programming); Psychiatry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001072152,0.0003569269,0.0004970661,0.0003084574,0.0001542371,0.0007025258,0.0003252879,0.0002903363,0.001293231],"category_scores_gemma":[0.002375096,0.0001717803,0.0005242269,0.0003528219,0.0002374151,0.0004007696,0.0003755941,0.0005957851,0.0002558134],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009656161,"about_ca_system_score_gemma":0.0009215438,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.007702401,"about_ca_topic_score_gemma":0.004523654,"domain_scores_codex":[0.9994741,0.0001804066,0.0000388082,0.00012724,0.0001327861,0.00004669988],"domain_scores_gemma":[0.9992704,0.0002241468,0.0002938727,0.00003996553,0.0001372282,0.00003442344],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.003991849,0.0001669744,0.827099,0.0009729934,0.0007685932,0.001591744,0.001250945,0.01319339,0.02376308,0.002111567,0.003832886,0.1212571],"study_design_scores_gemma":[0.0002713318,0.004969489,0.9208167,0.0004331476,0.0009662115,0.007748121,0.00133605,0.01619221,0.01764251,0.002134161,0.02734958,0.0001404994],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9748006,0.007806139,0.01063203,0.000287731,0.0000317257,0.000123867,0.00359625,0.0001467143,0.002574832],"genre_scores_gemma":[0.9872277,0.004193632,0.005695081,0.0001487688,0.00002740485,0.0001446652,0.001876016,0.00004156242,0.000645184],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007702401,"threshold_uncertainty_score":0.01531518,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1209277670052639,"score_gpt":0.4849760093186719,"score_spread":0.364048242313408,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}