{"id":"W3033245856","doi":"10.1093/jn/nxaa144","title":"The Cardioprotective Role of Flaxseed in the Prevention of Doxorubicin- and Trastuzumab-Mediated Cardiotoxicity in C57BL/6 Mice","year":2020,"lang":"en","type":"article","venue":"Journal of Nutrition","topic":"Phytoestrogen effects and research","field":"Medicine","cited_by":33,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Manitoba","funders":"University of Manitoba; Research Manitoba; Heart and Stroke Foundation of Canada","keywords":"Cardiotoxicity; Medicine; Ejection fraction; Doxorubicin; Trastuzumab; Pharmacology; Saline; Apoptosis; Chemotherapy; In vivo; Internal medicine; Breast cancer; Cancer; Endocrinology; Heart failure; Chemistry; Biochemistry; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001047793,0.00005991462,0.0003126906,0.0001026511,0.00002660586,0.000006489518,0.00007735224,0.00005631475,0.000001054636],"category_scores_gemma":[0.0003060799,0.0000326241,0.0001208329,0.0003277018,0.00007794012,0.00006706802,0.00001307859,0.0003741321,1.800241e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005319057,"about_ca_system_score_gemma":0.00007161337,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005609617,"about_ca_topic_score_gemma":0.0000168761,"domain_scores_codex":[0.998759,0.0003395711,0.0003632746,0.00006745053,0.0003649476,0.0001057179],"domain_scores_gemma":[0.9992919,0.0002351932,0.0002038177,0.00006393917,0.0001587623,0.00004638533],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001888832,0.0004903344,0.004922053,0.0003149463,0.00009881936,0.00004026465,0.00155248,0.0000259366,0.9869955,0.00002074419,0.00005732229,0.003592796],"study_design_scores_gemma":[0.01005771,0.006790323,0.4803202,0.001517077,0.0001581308,0.0003110931,0.008117585,0.001213799,0.4896176,0.001302584,0.0004997599,0.00009407748],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9940526,0.003500496,0.0000382834,0.00165841,0.00001907606,0.0006356809,0.000005551996,0.000001252558,0.00008864081],"genre_scores_gemma":[0.9989657,0.0008107607,0.00005213713,0.00002538299,0.0001283415,0.00001034251,0.00000154867,0.000004666547,0.000001132854],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4973778,"threshold_uncertainty_score":0.1625439,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01554674549347799,"score_gpt":0.2845172914611084,"score_spread":0.2689705459676304,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}