{"id":"W3033277959","doi":"10.1016/j.mito.2020.05.011","title":"High rate of hypertension in patients with m.3243A&gt;G MELAS mutations and POLG variants","year":2020,"lang":"en","type":"article","venue":"Mitochondrion","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia; Vancouver General Hospital; Simon Fraser University","funders":"","keywords":"MELAS syndrome; Heteroplasmy; Mitochondrial DNA; Internal medicine; Mitochondrial encephalomyopathy; Blood pressure; Lactic acidosis; Mitochondrial disease; Medicine; Chronic progressive external ophthalmoplegia; Biology; Cardiology; Genetics; Mitochondrial myopathy; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00004261149,0.0001153226,0.0001670671,0.00004767569,0.00003487278,0.000007487964,0.00006025709,0.0001198834,0.00003291158],"category_scores_gemma":[0.0001098719,0.00009775784,0.00002558314,0.0001302497,0.00005307787,0.000006714211,0.00004558703,0.0000744967,0.000008696285],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000004850635,"about_ca_system_score_gemma":0.00002920702,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003306827,"about_ca_topic_score_gemma":0.00003844705,"domain_scores_codex":[0.999223,0.00008196774,0.0001922301,0.0003006099,0.00007395363,0.0001282691],"domain_scores_gemma":[0.9995927,0.00001328371,0.00007799426,0.0001483591,0.00008961679,0.00007804007],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.001086636,0.0001187799,0.03175669,0.00001956184,0.00002674301,0.000007458291,0.0001516185,0.0001897729,0.9640293,0.0001819422,0.001635159,0.000796403],"study_design_scores_gemma":[0.01448071,0.005203095,0.7213361,0.00008778152,0.0001124253,0.00002363877,0.0001508366,0.000377179,0.2415409,0.0002074826,0.0157511,0.0007288249],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9971095,0.00006952053,0.001727199,0.0004519228,0.0002345391,0.0002421213,0.00002399299,0.00000811581,0.0001330911],"genre_scores_gemma":[0.9966319,0.00002692911,0.002186406,0.0006791728,0.0001031105,0.00001021584,0.0002358325,0.00001554213,0.0001109104],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7224883,"threshold_uncertainty_score":0.3986449,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009910726075486072,"score_gpt":0.1927830434957803,"score_spread":0.1828723174202942,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}