{"id":"W3033287977","doi":"10.21037/tlcr-20-154","title":"Patient-derived cell line, xenograft and organoid models in lung cancer therapy","year":2020,"lang":"en","type":"review","venue":"Translational Lung Cancer Research","topic":"Cancer Cells and Metastasis","field":"Medicine","cited_by":96,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; University Health Network","funders":"","keywords":"Medicine; Lung cancer; Organoid; Clearance; Clinical trial; Cancer; Cancer cell lines; Cancer therapy; Oncology; Bioinformatics; Cancer research; Cancer cell; Internal medicine; Biology; Neuroscience","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001343748,0.000730471,0.001286087,0.002031673,0.0002378415,0.00135675,0.0008986775,0.00118831,0.003480949],"category_scores_gemma":[0.00088814,0.0003046147,0.000672136,0.001585605,0.0005100012,0.001391624,0.000786867,0.00224082,0.00276356],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007227926,"about_ca_system_score_gemma":0.001054666,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009412882,"about_ca_topic_score_gemma":0.001921715,"domain_scores_codex":[0.9996878,0.00008090607,0.00004169751,0.00004306193,0.0001151326,0.00003148237],"domain_scores_gemma":[0.9995414,0.0002419606,0.00004419081,0.00001908762,0.000118627,0.00003464933],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001080114,0.0001491313,0.0002826292,0.0292775,0.0001107542,0.000291136,0.0001154648,0.0006620296,0.00738283,0.01106383,0.03824649,0.9123102],"study_design_scores_gemma":[0.00001095903,0.0001137238,0.000349389,0.002999492,0.00009955198,0.0007862921,0.00004156297,0.00009584746,0.001551367,0.001486989,0.9924468,0.0000181073],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001917365,0.9972874,0.0004101265,0.0002444884,0.0002384075,0.00002215639,0.00006278921,0.00001332162,0.001529606],"genre_scores_gemma":[0.0009547453,0.9975097,0.0004426932,0.0001813414,0.00008701295,0.00002499557,0.0001024252,0.000003883791,0.00069312],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003480949,"threshold_uncertainty_score":0.0116449,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.136169420596058,"score_gpt":0.4547635431572892,"score_spread":0.3185941225612313,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}