{"id":"W3033369584","doi":"10.1002/mus.26995","title":"Whole blood survival motor neuron protein levels correlate with severity of denervation in spinal muscular atrophy","year":2020,"lang":"en","type":"article","venue":"Muscle & Nerve","topic":"Neurogenetic and Muscular Disorders Research","field":"Medicine","cited_by":27,"is_retracted":false,"has_abstract":true,"ca_institutions":"Portage College","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institute of Child Health and Human Development; Cure SMA; Biogen","keywords":"Spinal muscular atrophy; Denervation; Motor neuron; Medicine; Atrophy; Progressive muscular atrophy; Lower motor neuron; Physical medicine and rehabilitation; Amyotrophic lateral sclerosis; Internal medicine; Disease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001856246,0.0001795089,0.0003591965,0.00009281734,0.00004010421,0.00001447188,0.0001419168,0.00008498703,0.00007039623],"category_scores_gemma":[0.000115007,0.0001568357,0.0001272993,0.0005065788,0.00008436072,0.00007715571,0.00008159758,0.0003404467,0.00001415599],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002066929,"about_ca_system_score_gemma":0.0001621104,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003159158,"about_ca_topic_score_gemma":0.00005675293,"domain_scores_codex":[0.9982106,0.0001619765,0.0003090666,0.0004070811,0.000595231,0.0003160411],"domain_scores_gemma":[0.9992602,0.00001411685,0.0000900412,0.0003071119,0.0001352517,0.0001932602],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.001800533,0.0008134503,0.04642923,0.0009563898,0.0001392222,0.0008705071,0.0005129303,0.0002390588,0.9338089,0.0001880213,0.00003351134,0.0142083],"study_design_scores_gemma":[0.004597229,0.003038617,0.9777416,0.0001578226,0.0000952903,0.00001458058,0.0001184283,0.001261916,0.01160644,0.00003232962,0.001152653,0.0001830691],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9962798,0.000243943,0.0005311248,0.001573643,0.00003220957,0.001072682,0.00001747055,0.00003407736,0.0002150333],"genre_scores_gemma":[0.9987845,0.00001037753,0.0006870649,0.0002123435,0.00006916765,0.00005489887,0.00002165362,0.00004104599,0.0001189318],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.9313124,"threshold_uncertainty_score":0.6395574,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03697874503891012,"score_gpt":0.2664837862600767,"score_spread":0.2295050412211666,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}