{"id":"W3033455367","doi":"10.3390/genes11060616","title":"G9a Is SETting the Stage for Colorectal Oncogenesis","year":2020,"lang":"en","type":"article","venue":"Genes","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"Natural Sciences and Engineering Research Council of Canada; Ontario Ministry of Research, Innovation and Science; Cancer Research Society","keywords":"Wnt signaling pathway; Colorectal cancer; Carcinogenesis; Cancer research; Biology; Oncology; Cancer; Genetics; Gene; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001587748,0.0003161652,0.0003491392,0.0005880329,0.0003385728,0.0005939337,0.0002437636,0.0008373951,0.003920231],"category_scores_gemma":[0.0006659949,0.0002230488,0.0002513118,0.0003500152,0.0003361313,0.0003092743,0.0003920427,0.0005982384,0.001221014],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004639793,"about_ca_system_score_gemma":0.0003760264,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001515219,"about_ca_topic_score_gemma":0.001639872,"domain_scores_codex":[0.9998215,0.00003525584,0.00001172316,0.00005116874,0.0000293466,0.00005107941],"domain_scores_gemma":[0.9996167,0.00004173035,0.00013253,0.00003116856,0.00004429861,0.0001334377],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003527921,0.0000864611,0.1171662,0.0003103342,0.000143716,0.003406843,0.0001998706,0.0002464681,0.836741,0.002809844,0.003310487,0.0320508],"study_design_scores_gemma":[0.00009023219,0.0009079929,0.7117828,0.0001131968,0.0002373061,0.008723672,0.0006284309,0.000958207,0.2156844,0.004186254,0.05661127,0.00007630845],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9729019,0.01355365,0.002523513,0.002451637,0.0002892496,0.0000609592,0.001278858,0.0004562968,0.00648389],"genre_scores_gemma":[0.9934403,0.002486957,0.0009486965,0.0002753951,0.00005716109,0.00001168047,0.0004409484,0.00003724818,0.002301669],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003920231,"threshold_uncertainty_score":0.01311445,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02289025695150656,"score_gpt":0.2757314392678255,"score_spread":0.252841182316319,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}