{"id":"W3033518311","doi":"10.1111/bjh.16812","title":"Severe macrothrombocytopenia with platelet CD9 deficiency responsive to romiplostim","year":2020,"lang":"en","type":"letter","venue":"British Journal of Haematology","topic":"Platelet Disorders and Treatments","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Children's Hospital of Michigan; Children’s Hospital of Michigan Foundation","keywords":"Eltrombopag; Bernard–Soulier syndrome; Romiplostim; Thrombopoietin receptor; Platelet; Platelet Glycoprotein GPIb-IX Complex; Ristocetin; Medicine; Platelet disorder; Thrombopoietin; Platelet membrane glycoprotein; Megakaryocyte; Platelet transfusion; Internal medicine; Bone marrow failure; Bone marrow; Mean platelet volume; Pediatrics; Gastroenterology; Von Willebrand factor; Biology; Genetics; Haematopoiesis","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009484939,0.0008209712,0.0004245777,0.0003929145,0.0002429554,0.0002149287,0.0002287196,0.0005981324,0.0009240523],"category_scores_gemma":[0.0004749283,0.0001641753,0.0002553495,0.0002669308,0.0002965372,0.0001995335,0.0002645847,0.0006120326,0.0003321622],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002374256,"about_ca_system_score_gemma":0.0001318595,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005483637,"about_ca_topic_score_gemma":0.0006303702,"domain_scores_codex":[0.9998385,0.0000321704,0.00002167066,0.00004011693,0.00003177047,0.00003570627],"domain_scores_gemma":[0.9998387,0.00005254162,0.00004077497,0.00001062884,0.00001211837,0.00004518714],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"case_report","study_design_gemma":"case_report","study_design_scores_codex":[0.0005469895,0.0001081451,0.03010636,0.0001779427,0.00005592013,0.8968165,0.0002284965,0.0003432597,0.0521924,0.0004490257,0.002054907,0.01692005],"study_design_scores_gemma":[0.00006814295,0.0005322425,0.05458942,0.00004064181,0.00005215935,0.9297178,0.00008001684,0.0009006978,0.009350376,0.0002649004,0.004390061,0.00001358704],"study_design_candidate":"case_report","study_design_consensus":"case_report","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9778968,0.005856669,0.003342831,0.001201613,0.0001482164,0.0001593178,0.0004737278,0.0003011421,0.01061982],"genre_scores_gemma":[0.9975148,0.0007885927,0.0005162288,0.0003428714,0.00007000397,0.00001446367,0.0001674651,0.00001794124,0.0005675118],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009240523,"threshold_uncertainty_score":0.003091276,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01540007665982929,"score_gpt":0.2566468440692635,"score_spread":0.2412467674094342,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}