{"id":"W3033683066","doi":"10.1186/s13054-020-02993-5","title":"Biomarkers of sepsis: time for a reappraisal","year":2020,"lang":"en","type":"review","venue":"Critical Care","topic":"Sepsis Diagnosis and Treatment","field":"Medicine","cited_by":699,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Michael's Hospital","funders":"","keywords":"Procalcitonin; Medicine; Sepsis; Biomarker; Intensive care medicine; Diagnostic biomarker; Internal medicine; Bioinformatics; Diagnostic accuracy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00004892587,0.0002946403,0.001941541,0.00008195532,0.00002811041,0.00001162789,0.00009164275,0.0002735407,0.0002336909],"category_scores_gemma":[0.001346141,0.0002136138,0.00116664,0.000164575,0.0001152324,0.00001513949,0.00004116755,0.0001261558,0.0001251476],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007121566,"about_ca_system_score_gemma":0.0003112995,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000003356887,"about_ca_topic_score_gemma":2.503489e-7,"domain_scores_codex":[0.9986718,0.00004907275,0.0004478947,0.0003995079,0.0002014524,0.0002302413],"domain_scores_gemma":[0.998064,0.001092132,0.0000610269,0.000307303,0.0002193837,0.0002561315],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00002667145,0.0001448982,0.000006606359,0.08014263,0.000632994,0.00009815286,0.00005049646,2.214002e-9,3.587278e-7,0.0008501806,0.01005794,0.9079891],"study_design_scores_gemma":[0.0004498727,0.0007500719,0.000008934763,0.01418423,0.008767711,0.0000282582,0.0001249979,0.000001392316,0.00001164537,0.0000185365,0.9754892,0.0001651439],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[9.14737e-7,0.9932757,0.00001148685,0.0007248507,0.0001384456,0.001155285,0.000729323,0.00004423936,0.00391977],"genre_scores_gemma":[0.0001282009,0.9966434,0.001247543,0.0002100186,0.0002515129,0.0005884955,0.0008224716,0.00007291218,0.00003546763],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9654313,"threshold_uncertainty_score":0.8710917,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1878332716133546,"score_gpt":0.4819430444594349,"score_spread":0.2941097728460803,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}