{"id":"W3033778638","doi":"10.1177/1753425920929759","title":"Poor stimulation of bovine dendritic cells by <i>Mycobacterium bovis</i> culture supernatant and surface extract is associated with decreased activation of ERK and NF- <b>κ</b> B and higher expression of SOCS1 and 3","year":2020,"lang":"en","type":"article","venue":"Innate Immunity","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"Genome British Columbia; Genome Prairie; Banting Research Foundation; Ministry of Agriculture - Saskatchewan; Genome Canada","keywords":"MAPK/ERK pathway; Mycobacterium bovis; Stimulation; Cell biology; Chemistry; Microbiology; Apoptosis; NF-κB; Biology; Molecular biology; Signal transduction; Medicine; Biochemistry; Mycobacterium tuberculosis","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001146786,0.0004220369,0.000360507,0.0001181851,0.0001379296,0.0003553863,0.0001116768,0.0002130841,0.001160218],"category_scores_gemma":[0.0001603709,0.0001109852,0.0003272337,0.000158513,0.0001562271,0.0001794434,0.0002046637,0.0005565757,0.0004967308],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001712927,"about_ca_system_score_gemma":0.0001328154,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005859411,"about_ca_topic_score_gemma":0.0008186661,"domain_scores_codex":[0.9997494,0.00004770298,0.00002903189,0.0000438782,0.00005873098,0.00007120899],"domain_scores_gemma":[0.9998841,0.00003363573,0.00002445946,0.00001909981,0.00001910581,0.00001958409],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005159768,0.0000135617,0.0001146662,0.00002108462,0.000001869656,0.00001007722,0.000007022235,0.000007113228,0.9994369,0.000007686804,0.00001018425,0.0003182079],"study_design_scores_gemma":[0.000006133565,0.0002699401,0.004626499,0.000004779059,0.000009541745,0.0001275354,0.00002875031,0.0001704221,0.9935535,0.00001265003,0.001187501,0.000002590078],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9940591,0.001764462,0.001822355,0.0001135457,0.00005137832,0.0000197469,0.0005499349,0.00002745704,0.001592087],"genre_scores_gemma":[0.9949137,0.0006590162,0.001490634,0.00008218599,0.00002019715,0.00002290085,0.001426371,0.00001527721,0.001369688],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001160218,"threshold_uncertainty_score":0.003881276,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01092635654842149,"score_gpt":0.2233957749637887,"score_spread":0.2124694184153673,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}