{"id":"W3033800777","doi":"10.1136/annrheumdis-2020-eular.852","title":"SAT0402 EFFICACY AND SAFETY OF GUSELKUMAB, A MONOCLONAL ANTIBODY SPECIFIC TO THE P19-SUBUNIT OF INTERLEUKIN-23, THROUGH WEEK 52 OF A PHASE 3, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED STUDY CONDUCTED IN BIOLOGIC-NAÏVE PATIENTS WITH ACTIVE PSORIATIC ARTHRITIS","year":2020,"lang":"en","type":"article","venue":"Annals of the Rheumatic Diseases","topic":"Pharmaceutical studies and practices","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":false,"ca_institutions":"Memorial University of Newfoundland","funders":"","keywords":"Medicine; Placebo; Axial spondyloarthritis; Internal medicine; Pathology; Alternative medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006406315,0.0002757472,0.002013546,0.0000769058,0.00007263057,0.00001264688,0.0002912202,0.00004086545,0.0001043135],"category_scores_gemma":[0.002158864,0.000133608,0.0002577087,0.0005110891,0.0005037918,0.0001455439,0.0002043761,0.0001887181,0.000001840601],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001191805,"about_ca_system_score_gemma":0.00008706927,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001505347,"about_ca_topic_score_gemma":0.00002154445,"domain_scores_codex":[0.996972,0.0007623035,0.001238655,0.0002838473,0.0005065833,0.0002366573],"domain_scores_gemma":[0.9946464,0.003402603,0.00108084,0.0003419056,0.0003833977,0.0001448617],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9658637,0.006852261,0.002728891,0.0003405067,0.00340058,0.000004222915,0.008709697,0.00008713783,0.00009467811,0.00006700721,0.0002669521,0.01158437],"study_design_scores_gemma":[0.9564186,0.005263446,0.02679004,0.001778427,0.001647744,0.000001921696,0.006310068,0.0003004554,0.000973739,0.0001560615,0.0001593159,0.0002001778],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9859369,0.003091322,0.00003345801,0.003508773,0.0000583065,0.006968645,0.000264434,0.000009547973,0.0001286471],"genre_scores_gemma":[0.9966901,0.002760748,0.00005846743,0.0003006487,0.00001965625,0.000121125,0.00002752077,0.00001522521,0.000006528809],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02406115,"threshold_uncertainty_score":0.5448376,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.118826445573371,"score_gpt":0.3937381328853905,"score_spread":0.2749116873120195,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}