{"id":"W3033814020","doi":"10.1097/tp.0000000000003278","title":"Impact of Belatacept Conversion on Renal Function, Histology, and Gene Expression in Kidney Transplant Patients With Chronic Active Antibody-mediated Rejection","year":2020,"lang":"en","type":"article","venue":"Transplantation","topic":"Renal Transplantation Outcomes and Treatments","field":"Medicine","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"The Metabolomics Innovation Centre","funders":"","keywords":"Belatacept; Medicine; Calcineurin; Interquartile range; Urology; Tacrolimus; Renal function; Immunosuppression; Internal medicine; Biopsy; Prospective cohort study; Kidney transplantation; Gastroenterology; Histology; Kidney; Cohort; Transplantation; Kidney transplant","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000037501,0.0002032814,0.0003144573,0.0001785569,0.00005318357,0.000004716915,0.00003011248,0.0001169803,0.00008672561],"category_scores_gemma":[0.000007151623,0.0001460733,0.00007153332,0.0002365057,0.00005763628,0.0001846207,0.00000172572,0.0001700211,0.000007706069],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001334711,"about_ca_system_score_gemma":0.0001098686,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001184905,"about_ca_topic_score_gemma":0.00001762599,"domain_scores_codex":[0.9989005,0.00006468617,0.0002918192,0.0003171525,0.0002584988,0.0001673248],"domain_scores_gemma":[0.99945,0.00006823627,0.000134879,0.00008681654,0.00007019957,0.000189842],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0310808,0.0003246081,0.7789904,0.0006771146,0.0001697265,0.00006831202,0.001621471,0.0002992794,0.18631,0.000007347785,0.000008750623,0.0004421597],"study_design_scores_gemma":[0.01753308,0.004929007,0.925847,0.001120861,0.0003356127,0.00002515966,0.00001439681,0.000212875,0.04984145,0.000003100669,0.000006642433,0.0001307925],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9941298,0.00005112225,0.004479081,0.0001194705,0.00004666271,0.0006057757,0.0004453252,0.00003609154,0.00008662651],"genre_scores_gemma":[0.9942222,0.0006550185,0.0002631509,0.0001186246,0.00002186214,0.00001234965,0.00467942,0.00001947473,0.000007907184],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1468566,"threshold_uncertainty_score":0.5956698,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0106673333802742,"score_gpt":0.2624900896351495,"score_spread":0.2518227562548753,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}