{"id":"W3033814020","doi":"10.1097/tp.0000000000003278","title":"Impact of Belatacept Conversion on Renal Function, Histology, and Gene Expression in Kidney Transplant Patients With Chronic Active Antibody-mediated Rejection","year":2020,"lang":"en","type":"article","venue":"Transplantation","topic":"Renal Transplantation Outcomes and Treatments","field":"Medicine","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"The Metabolomics Innovation Centre","funders":"","keywords":"Belatacept; Medicine; Calcineurin; Interquartile range; Urology; Tacrolimus; Renal function; Immunosuppression; Internal medicine; Biopsy; Prospective cohort study; Kidney transplantation; Gastroenterology; Histology; Kidney; Cohort; Transplantation; Kidney transplant","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002830606,0.0001864761,0.0002796638,0.0001830462,0.0003201218,0.0006040725,0.000260935,0.0001551776,0.0004977875],"category_scores_gemma":[0.00214549,0.00008872723,0.0002170348,0.0001835366,0.0003058914,0.0002225729,0.0004085203,0.0003173526,0.0001208],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004721851,"about_ca_system_score_gemma":0.0004447387,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004016803,"about_ca_topic_score_gemma":0.0006111967,"domain_scores_codex":[0.9988489,0.0007130602,0.00009392769,0.0001269582,0.000126895,0.00009021428],"domain_scores_gemma":[0.9985734,0.0004772113,0.0004107674,0.0001773701,0.0001133891,0.0002477621],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.02112599,0.002003168,0.9180657,0.00006910427,0.0001367067,0.0006262673,0.0003995147,0.0006300149,0.01720086,0.00006575989,0.000125373,0.03955144],"study_design_scores_gemma":[0.001051941,0.04325441,0.9404633,0.00001932278,0.000166297,0.002219452,0.0003158242,0.001031175,0.01006951,0.00005658231,0.001336798,0.00001538394],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9995095,0.0001551344,0.0001341848,0.000008686053,0.000002440937,0.00003043776,0.00001717347,0.000002233377,0.0001404066],"genre_scores_gemma":[0.9995522,0.00003788065,0.0002455187,0.00002239309,0.000004513868,0.00002815601,0.00007291973,0.000001077532,0.00003535484],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002830606,"threshold_uncertainty_score":0.01496989,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0106673333802742,"score_gpt":0.2624900896351495,"score_spread":0.2518227562548753,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}