{"id":"W3033869738","doi":"10.3390/v12060610","title":"Differential Effects of Human Adenovirus E1A Protein Isoforms on Aerobic Glycolysis in A549 Human Lung Epithelial Cells","year":2020,"lang":"en","type":"article","venue":"Viruses","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":26,"is_retracted":false,"has_abstract":true,"ca_institutions":"Lawson Health Research Institute; McGill University Health Centre; University of Manitoba; Western University","funders":"Canadian Institutes of Health Research","keywords":"Biology; Cell biology; Warburg effect; Anaerobic glycolysis; Glycolysis; Reprogramming; Viral replication; Cell; Cell culture; Metabolism; Biochemistry; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002554318,0.0002389453,0.0003478322,0.000238246,0.000182718,0.0002992227,0.0001072042,0.0002166655,0.0009356763],"category_scores_gemma":[0.0001500647,0.0001382663,0.0004311516,0.0003699058,0.000187851,0.0002024035,0.0001751024,0.0003839195,0.0002333451],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002928098,"about_ca_system_score_gemma":0.0002010218,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002104286,"about_ca_topic_score_gemma":0.002161578,"domain_scores_codex":[0.9996281,0.00007217752,0.00005564743,0.00009092996,0.00007661972,0.00007655566],"domain_scores_gemma":[0.9998481,0.00004780242,0.00002303559,0.00002312703,0.00002802037,0.00002993294],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002375684,0.00004478757,0.0003651805,0.00003252351,0.000006690888,0.00002820335,0.00003493479,0.00005160409,0.9986205,0.00004623603,0.00002367881,0.0005080253],"study_design_scores_gemma":[0.00002687331,0.000918549,0.02104375,0.000009290499,0.00003011618,0.0001425851,0.0002060701,0.00159379,0.9742646,0.00005044555,0.001701536,0.00001246432],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9947847,0.001578959,0.00126042,0.00007537755,0.00004491951,0.00003399448,0.001176638,0.00002417997,0.001020842],"genre_scores_gemma":[0.9924195,0.001296332,0.002515551,0.00007356897,0.00001111993,0.0000709893,0.0016732,0.00001395081,0.001925727],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002104286,"threshold_uncertainty_score":0.004184067,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01839091968548596,"score_gpt":0.294353714086078,"score_spread":0.2759627944005921,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}