{"id":"W3033869738","doi":"10.3390/v12060610","title":"Differential Effects of Human Adenovirus E1A Protein Isoforms on Aerobic Glycolysis in A549 Human Lung Epithelial Cells","year":2020,"lang":"en","type":"article","venue":"Viruses","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":26,"is_retracted":false,"has_abstract":true,"ca_institutions":"Lawson Health Research Institute; McGill University Health Centre; University of Manitoba; Western University","funders":"Canadian Institutes of Health Research","keywords":"Biology; Cell biology; Warburg effect; Anaerobic glycolysis; Glycolysis; Reprogramming; Viral replication; Cell; Cell culture; Metabolism; Biochemistry; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00009764844,0.0002793357,0.0003515436,0.0001374422,0.0001147225,0.00003114822,0.0004548425,0.0001991882,0.0002097183],"category_scores_gemma":[0.00005262806,0.0002513111,0.0001647834,0.0002331711,0.0001406458,0.000007748365,0.0001833878,0.0002390347,0.00004775147],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003264256,"about_ca_system_score_gemma":0.00006315779,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001258693,"about_ca_topic_score_gemma":0.0001980948,"domain_scores_codex":[0.998161,0.0001881306,0.0003683417,0.0005211652,0.0003359588,0.0004254121],"domain_scores_gemma":[0.9992113,0.00002294742,0.0001295702,0.0004452762,0.00004471634,0.0001462572],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001845584,0.0002920653,0.0005119499,0.0001742234,0.00009801637,0.00001597306,0.0001237591,0.00004101484,0.9957944,0.00004282571,0.0002474484,0.0008127959],"study_design_scores_gemma":[0.001944585,0.006452113,0.0006677798,0.00005484863,0.00002117121,2.706505e-7,0.00001626611,0.00001977327,0.9901618,0.00003081275,0.0003657806,0.0002648243],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9986467,0.0002002951,0.00004401018,0.00005129898,0.00005795638,0.0008327801,0.00004030445,0.00002368483,0.0001029819],"genre_scores_gemma":[0.9988381,0.0000446802,0.00002064306,0.0004280411,0.0003147839,0.0001188949,0.00004692915,0.00005877754,0.0001291091],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006160048,"threshold_uncertainty_score":0.9999939,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01839091968548596,"score_gpt":0.294353714086078,"score_spread":0.2759627944005921,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}