{"id":"W3033936146","doi":"10.1016/j.mayocp.2020.01.039","title":"Efficacy and Safety of Tofacitinib, Baricitinib, and Upadacitinib for Rheumatoid Arthritis: A Systematic Review and Meta-Analysis","year":2020,"lang":"en","type":"review","venue":"Mayo Clinic Proceedings","topic":"Rheumatoid Arthritis Research and Therapies","field":"Medicine","cited_by":108,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Sun Pharma; Sichuan Province Science and Technology Support Program; Bristol-Myers Squibb Canada; Boehringer Ingelheim; Chengdu Science and Technology Bureau; National Natural Science Foundation of China; Ministry of Science and Technology of the People's Republic of China; Pfizer","keywords":"Medicine; Tofacitinib; Rheumatoid arthritis; Meta-analysis; Systematic review; MEDLINE; Internal medicine","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.006538064,0.002607169,0.01631107,0.003958993,0.0004792993,0.002579447,0.001890951,0.001844615,0.003766493],"category_scores_gemma":[0.01359799,0.001368025,0.03333043,0.004978305,0.0006149661,0.001533453,0.001496648,0.001982055,0.0003934188],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00196596,"about_ca_system_score_gemma":0.002652427,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.006649958,"about_ca_topic_score_gemma":0.0208111,"domain_scores_codex":[0.9963242,0.001257497,0.001259031,0.0004804973,0.0004878172,0.0001910582],"domain_scores_gemma":[0.9943238,0.003683404,0.001170589,0.0002118204,0.000487763,0.0001226024],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"meta_analysis","study_design_gemma":"meta_analysis","study_design_scores_codex":[0.003460167,0.00003894953,0.002560896,0.3211874,0.6559288,0.0001110691,0.00007355137,0.0003759348,0.0003536973,0.0001071874,0.0007230759,0.01507924],"study_design_scores_gemma":[0.0008943786,0.0001575174,0.002326262,0.009492804,0.9855864,0.00006582453,0.00003367366,0.00008673299,0.00007744097,0.0001035295,0.001152741,0.00002276565],"study_design_candidate":"meta_analysis","study_design_consensus":"meta_analysis","genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.004490989,0.9941784,0.0003295619,0.000109028,0.000115726,0.0001439732,0.0004220658,0.00001864832,0.0001916435],"genre_scores_gemma":[0.1221577,0.8736672,0.00143938,0.0008976331,0.0002060924,0.0003852525,0.0007703492,0.00002594807,0.0004503673],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.01631107,"threshold_uncertainty_score":0.03457701,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08640359366624471,"score_gpt":0.3755306776758248,"score_spread":0.28912708400958,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}