{"id":"W3033940508","doi":"10.1097/j.pain.0000000000001952","title":"Interpretation of chronic pain clinical trial outcomes: IMMPACT recommended considerations","year":2020,"lang":"en","type":"article","venue":"Pain","topic":"Health Systems, Economic Evaluations, Quality of Life","field":"Economics, Econometrics and Finance","cited_by":181,"is_retracted":false,"has_abstract":true,"ca_institutions":"Public Health Ontario; University of Toronto","funders":"Daiichi Sankyo Europe; National Institute of Allergy and Infectious Diseases; U.S. Food and Drug Administration; National Institutes of Health; Astellas Pharma; Voyager Therapeutics; ACADIA Pharmaceuticals; Celgene; PTC Therapeutics; New York State Stem Cell Science; University of Washington; Eli Lilly and Company; Allergan; AstraZeneca; Multiple Sclerosis Society; Novartis Pharmaceuticals Corporation; Administration for Community Living; Depomed; Alnylam Pharmaceuticals; Alexion Pharmaceuticals; National Institute on Aging; aTyr; Amgen; Biogen; Pfizer; Washington State University; GlaxoSmithKline","keywords":"Randomized controlled trial; Medicine; Analgesic; Clinical trial; Chronic pain; Addiction; Physical therapy; Intensive care medicine; Medical physics; Psychiatry; Surgery; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaresearch","insufficient_payload"],"consensus_categories":["metaresearch"],"category_scores_codex":[0.08880366,0.0001643258,0.001182463,0.0001370484,0.00009610481,0.00005068206,0.000172073,0.0001592367,0.0014419],"category_scores_gemma":[0.1009973,0.0001986347,0.0002996757,0.0001376768,0.00006080781,0.0002571574,0.00003454744,0.0002311565,0.000756447],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002888338,"about_ca_system_score_gemma":0.0002906878,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001602363,"about_ca_topic_score_gemma":0.0001023372,"domain_scores_codex":[0.9878991,0.005195701,0.006067972,0.0004846918,0.00007893475,0.0002735785],"domain_scores_gemma":[0.9817988,0.01512465,0.002417639,0.0003772541,0.00005841953,0.0002231907],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"simulation_or_modeling","study_design_scores_codex":[0.002619077,0.00138172,0.2064137,0.001538754,0.001139458,0.000004913632,0.01557191,0.00135365,0.00001533975,0.1530477,0.5898651,0.02704867],"study_design_scores_gemma":[0.03601138,0.003301227,0.01092265,0.0001917811,0.00003961303,0.0000015365,0.002513052,0.8287961,0.00001164173,0.04939764,0.06787414,0.0009392335],"study_design_candidate":"simulation_or_modeling","study_design_consensus":null,"genre_codex":"methods","genre_gemma":"empirical","genre_scores_codex":[0.07000257,0.001337089,0.5227401,0.3959012,0.002134952,0.003133978,0.000475973,0.0001924611,0.004081715],"genre_scores_gemma":[0.9488667,0.00004015872,0.002922545,0.04737062,0.0005651706,0.00008514702,0.00005455515,0.00002580558,0.00006933684],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.8788641,"threshold_uncertainty_score":0.9994709,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.5825172514771687,"score_gpt":0.5104653602336494,"score_spread":0.0720518912435193,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}