{"id":"W3034037943","doi":"10.1111/bjh.16793","title":"Early relapse after high‐dose melphalan autologous stem cell transplant predicts inferior survival and is associated with high disease burden and genetically high‐risk disease in multiple myeloma","year":2020,"lang":"en","type":"article","venue":"British Journal of Haematology","topic":"Multiple Myeloma Research and Treatments","field":"Medicine","cited_by":51,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Merck Sharp and Dohme; Myeloma UK; University of Leeds; National Institute for Health and Care Research; Institute of Cancer Research; Cancer Research UK; Royal Marsden NHS Foundation Trust; National Cancer Research Institute; Celgene; University of Birmingham; Cancer Research Institute","keywords":"Medicine; Multiple myeloma; Melphalan; Oncology; Stem cell; Internal medicine; Disease; Transplantation; Overall survival; Surgery; Biology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002519417,0.000287657,0.001024044,0.0001565604,0.00008834283,0.00007868169,0.0001273134,0.0001584819,0.00006421065],"category_scores_gemma":[0.0003317583,0.000253225,0.00009384964,0.0001608082,0.0003044382,0.0001703416,0.00007527244,0.0006201131,0.000005264545],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005255555,"about_ca_system_score_gemma":0.0003307154,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009134391,"about_ca_topic_score_gemma":0.0003804764,"domain_scores_codex":[0.9972821,0.0005431475,0.0006616405,0.0004448307,0.0005379087,0.0005303525],"domain_scores_gemma":[0.997302,0.0003836096,0.0002780751,0.0001606363,0.0001962284,0.001679475],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.009894913,0.0003042224,0.6724575,0.0002368545,0.0003384035,0.3112307,0.0005970983,0.00001206294,0.00006822503,0.00001406858,0.00004251942,0.004803541],"study_design_scores_gemma":[0.01883609,0.001530395,0.9710174,0.00078038,0.0005829721,0.006117986,0.00006573605,0.0006788816,0.00007610033,0.00008259099,0.00001539915,0.0002161083],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.991069,0.004175833,0.00006152958,0.00324897,0.00006521251,0.0005869006,0.0007534839,0.00003193172,0.000007194126],"genre_scores_gemma":[0.9968019,0.002311319,0.0004130377,0.00023213,0.00007394994,0.00003355713,0.00005575896,0.0000498527,0.00002854638],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3051127,"threshold_uncertainty_score":0.999992,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01162331094242796,"score_gpt":0.224951247851477,"score_spread":0.2133279369090491,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}