{"id":"W3034085749","doi":"10.1186/s40168-020-00839-4","title":"Re-evaluating the relationship between missing heritability and the microbiome","year":2020,"lang":"en","type":"letter","venue":"Microbiome","topic":"Genetic Associations and Epidemiology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":25,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dalhousie University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Microbiome; Heritability; Biology; Trait; Missing heritability problem; Genetic association; Genetic variation; Evolutionary biology; Genome-wide association study; Population; Variation (astronomy); Genetics; Genetic variants; Gene; Single-nucleotide polymorphism; Demography; Computer science; Genotype","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001554274,0.0003346834,0.0004634138,0.00004064124,0.000621326,0.00009713454,0.0004984877,0.0007789256,0.00001759513],"category_scores_gemma":[0.001719438,0.0002102756,0.0002370078,0.0001897234,0.0007681376,0.000002566904,0.0003830542,0.001002329,0.00002959027],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004284465,"about_ca_system_score_gemma":0.0001230473,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006674048,"about_ca_topic_score_gemma":0.00001315247,"domain_scores_codex":[0.9968418,0.001387084,0.000569157,0.0006619801,0.0001079404,0.0004319622],"domain_scores_gemma":[0.9975388,0.001214675,0.0003978761,0.0007137917,0.00008882899,0.00004600228],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00003583604,0.000006959043,0.03363474,0.0001079874,0.0002138209,0.00000320304,0.00031448,0.000002690804,0.04994424,0.000007054804,0.9149989,0.0007301031],"study_design_scores_gemma":[0.001279996,0.0002060244,0.05337836,0.00006115274,0.0004074418,0.00004091189,0.0001765436,0.00003477776,0.0008554665,0.00220128,0.9406958,0.0006622315],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"empirical","genre_scores_codex":[0.1528052,0.002259354,0.0003547545,0.8433717,0.0002158557,0.0005771072,0.0002218454,0.00001972024,0.0001744407],"genre_scores_gemma":[0.5142376,0.00006265435,0.002464891,0.4738744,0.004291596,0.00007346715,0.002844652,0.00009245151,0.002058324],"genre_candidate":"commentary","genre_consensus":null,"teacher_disagreement_score":0.3694973,"threshold_uncertainty_score":0.8574792,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06849121391312539,"score_gpt":0.3212659082611524,"score_spread":0.252774694348027,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}