{"id":"W3034085749","doi":"10.1186/s40168-020-00839-4","title":"Re-evaluating the relationship between missing heritability and the microbiome","year":2020,"lang":"en","type":"letter","venue":"Microbiome","topic":"Genetic Associations and Epidemiology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":25,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dalhousie University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Microbiome; Heritability; Biology; Trait; Missing heritability problem; Genetic association; Genetic variation; Evolutionary biology; Genome-wide association study; Population; Variation (astronomy); Genetics; Genetic variants; Gene; Single-nucleotide polymorphism; Demography; Computer science; Genotype","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01241899,0.0005233281,0.0007818867,0.001154086,0.001568341,0.001995164,0.001476351,0.01012729,0.006488097],"category_scores_gemma":[0.1083332,0.0003130029,0.0006588883,0.000889615,0.00231108,0.003244612,0.001203086,0.01454099,0.004416671],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.003112294,"about_ca_system_score_gemma":0.001982011,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01090454,"about_ca_topic_score_gemma":0.01295662,"domain_scores_codex":[0.9930778,0.003956818,0.0005168685,0.0008296065,0.001302223,0.0003167884],"domain_scores_gemma":[0.9204367,0.06233332,0.002579699,0.003137942,0.009771327,0.001741016],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.0002323526,0.00004353793,0.01459192,0.0002502364,0.0001040083,0.003089443,0.0005532382,0.0004045283,0.0009734277,0.01290796,0.7988524,0.1679971],"study_design_scores_gemma":[0.0002530554,0.0002471418,0.02629831,0.00194159,0.0002887675,0.0187033,0.002215046,0.007968202,0.002265738,0.2155542,0.7240551,0.0002095422],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.002881767,0.004108674,0.004377411,0.9735377,0.01155005,0.00002090198,0.0002635977,0.00009782197,0.003162128],"genre_scores_gemma":[0.08504387,0.009579537,0.01181764,0.8105631,0.07394273,0.0001381292,0.0003717809,0.0001874062,0.008355918],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.01241899,"threshold_uncertainty_score":0.06567872,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06849121391312539,"score_gpt":0.3212659082611524,"score_spread":0.252774694348027,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}