{"id":"W3034412186","doi":"10.1002/pro.3898","title":"The long form of <scp>pVHL</scp> is artifactually modified by serine protease inhibitor <scp>AEBSF</scp>","year":2020,"lang":"en","type":"article","venue":"Protein Science","topic":"Cancer, Hypoxia, and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; University Health Network; University of Toronto","funders":"Canadian Institutes of Health Research; University of Toronto","keywords":"Serine protease; Gene isoform; Chemistry; Protease; Serine; Protease inhibitor (pharmacology); Biochemistry; Alternative splicing; Molecular biology; Cell biology; Biology; Enzyme; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002717999,0.0004246481,0.0001928236,0.000267179,0.0002143892,0.0002634042,0.0003081855,0.0002751311,0.00222256],"category_scores_gemma":[0.0003756373,0.0001495415,0.0002549945,0.0002165816,0.0003537934,0.0002334546,0.0002108927,0.0006152519,0.0007791043],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004412273,"about_ca_system_score_gemma":0.0003344016,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001284508,"about_ca_topic_score_gemma":0.001157416,"domain_scores_codex":[0.9996911,0.00006365035,0.00002733759,0.00006160996,0.00009194174,0.00006438971],"domain_scores_gemma":[0.9995244,0.0001134904,0.0001548861,0.00007188709,0.00004405708,0.00009132217],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007506338,0.00001492296,0.0001075148,0.00001429746,0.000007627297,0.00008294025,0.000006556419,0.00001903036,0.9989138,0.00009037161,0.00005944183,0.0006085607],"study_design_scores_gemma":[0.00000635202,0.00006416065,0.003156555,0.0000047307,0.000006460701,0.000510929,0.00001122236,0.0003428626,0.9931392,0.00003941173,0.002714659,0.000003331089],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9861549,0.00159188,0.00788806,0.0002738898,0.0001091669,0.0000310532,0.0005122481,0.0001687549,0.003269989],"genre_scores_gemma":[0.9818692,0.0009335003,0.007029942,0.0001996622,0.00003436074,0.00004724984,0.002324524,0.0001265266,0.007435033],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00222256,"threshold_uncertainty_score":0.007435203,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01309838532700811,"score_gpt":0.2409879624613946,"score_spread":0.2278895771343865,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}