{"id":"W3034465931","doi":"10.3233/jpd-202085","title":"Crosstalk Between Alpha-Synuclein and Other Human and Non-Human Amyloidogenic Proteins: Consequences for Amyloid Formation in Parkinson’s Disease","year":2020,"lang":"en","type":"review","venue":"Journal of Parkinson s Disease","topic":"Parkinson's Disease Mechanisms and Treatments","field":"Medicine","cited_by":41,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Fondation Chalmers; Vetenskapsrådet; Knut och Alice Wallenbergs Stiftelse","keywords":"Alpha-synuclein; Parkinson's disease; Amyloid (mycology); Crosstalk; Microbiome; Protein aggregation; Biology; Disease; Chemistry; Neuroscience; Biochemistry; Medicine; Bioinformatics; Internal medicine","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005521404,0.000923697,0.002864848,0.0007272367,0.0003269541,0.000256821,0.000303386,0.0002735717,0.00006163202],"category_scores_gemma":[0.0002198735,0.0007313653,0.001009467,0.0003339948,0.0003224528,0.0004774484,0.0001223153,0.000554397,0.00001061705],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004362151,"about_ca_system_score_gemma":0.0008609737,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003443237,"about_ca_topic_score_gemma":0.00001960591,"domain_scores_codex":[0.9956697,0.0002845042,0.001896197,0.0008064019,0.0007287281,0.000614457],"domain_scores_gemma":[0.9950653,0.0001451572,0.001862299,0.0004331551,0.0001798758,0.002314209],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.005113659,0.003564754,0.08555498,0.1134629,0.005056515,0.01375152,0.0009504542,0.000002190813,0.0003988043,0.000505174,0.001894878,0.7697442],"study_design_scores_gemma":[0.005633933,0.0008912473,0.02623254,0.01452058,0.007281284,0.000143942,0.00006075245,0.00002285771,0.00002695706,0.0011029,0.9434063,0.0006766993],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.09035337,0.9032385,0.0001098589,0.0002755958,0.0001046719,0.004106931,0.001737011,0.00003763972,0.00003645694],"genre_scores_gemma":[0.398104,0.5995177,0.0004518234,0.0002477788,0.0006663057,0.000546233,0.000238489,0.0001615838,0.00006614915],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9415115,"threshold_uncertainty_score":0.9995137,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06322794377711702,"score_gpt":0.3603085608000225,"score_spread":0.2970806170229056,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}