{"id":"W3034555975","doi":"10.3390/cells9061436","title":"Sex Chromosomes and Sex Phenotype Contribute to Biased DNA Methylation in Mouse Liver","year":2020,"lang":"en","type":"article","venue":"Cells","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":24,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University Health Centre; Ontario Genomics; McGill University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Fonds de Recherche du Québec - Santé; Genome Canada","keywords":"Biology; DNA methylation; Dosage compensation; Genetics; Methylation; Gene; Epigenetics; Phenotype; Sexual dimorphism; Chromosome; Y chromosome; Gene expression","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001274261,0.00009788454,0.0001217274,0.00002848541,0.00002625691,0.00002119855,0.00006281697,0.00009814059,0.0000196954],"category_scores_gemma":[0.00006419233,0.0001006347,0.00002492285,0.00008442862,0.00001771984,0.000002859253,0.00006089899,0.0000473963,0.00001862553],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000008169705,"about_ca_system_score_gemma":0.00002076068,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001688762,"about_ca_topic_score_gemma":0.00001929825,"domain_scores_codex":[0.9993262,0.00005613101,0.0001413984,0.0002638401,0.00007237604,0.0001400308],"domain_scores_gemma":[0.9996726,0.00001966313,0.00003717533,0.0001238335,0.00003017698,0.0001165443],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002169136,0.0000149854,0.001110186,0.00001313168,0.00000925586,0.000002163704,0.0002563899,0.0003199229,0.993664,0.000006933374,0.0002023371,0.004378987],"study_design_scores_gemma":[0.0004133082,0.0001750823,0.001266936,0.000003048166,0.000006279042,1.084444e-7,0.00002997702,0.0006979373,0.9791852,0.00002575313,0.01806941,0.000127009],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9946018,0.001497632,0.003106354,0.0002468163,0.00003868717,0.0002106958,0.00002847079,0.000008959582,0.0002605547],"genre_scores_gemma":[0.9977385,0.0004314348,0.000629715,0.000535387,0.0001350707,0.000006889302,0.00007821385,0.000014517,0.0004302643],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01786708,"threshold_uncertainty_score":0.4103765,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01654739946651534,"score_gpt":0.2417474813961368,"score_spread":0.2252000819296215,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}