{"id":"W3034555975","doi":"10.3390/cells9061436","title":"Sex Chromosomes and Sex Phenotype Contribute to Biased DNA Methylation in Mouse Liver","year":2020,"lang":"en","type":"article","venue":"Cells","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":24,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University Health Centre; Ontario Genomics; McGill University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Fonds de Recherche du Québec - Santé; Genome Canada","keywords":"Biology; DNA methylation; Dosage compensation; Genetics; Methylation; Gene; Epigenetics; Phenotype; Sexual dimorphism; Chromosome; Y chromosome; Gene expression","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002356293,0.0002234112,0.0001846495,0.0008199618,0.0001036697,0.000262685,0.0001300891,0.0002448131,0.001624494],"category_scores_gemma":[0.0001798641,0.0002627173,0.000293562,0.0002503273,0.0002547442,0.0001340801,0.0002363994,0.0002709636,0.0002333834],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001184019,"about_ca_system_score_gemma":0.0001316125,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003778925,"about_ca_topic_score_gemma":0.0008085126,"domain_scores_codex":[0.9998283,0.00003330465,0.00001549088,0.00005343606,0.00003714499,0.00003219908],"domain_scores_gemma":[0.999796,0.00003492645,0.00008799604,0.00002688559,0.00001721017,0.0000371671],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000190824,0.000007067597,0.003643892,0.00002166326,0.00001122314,0.00004198287,0.0000262539,0.00004319477,0.994121,0.00008431058,0.00001672175,0.001791784],"study_design_scores_gemma":[0.00004097221,0.0003026247,0.2550339,0.00002018888,0.00007938004,0.001057541,0.00008612211,0.001006495,0.7393554,0.0004314285,0.002567146,0.00001873988],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9941397,0.001439476,0.002644955,0.00005261528,0.00001109065,0.00001108031,0.0005543625,0.00005222674,0.001094471],"genre_scores_gemma":[0.9940575,0.000776229,0.001747274,0.00007339512,0.000007223577,0.00003993202,0.0006664455,0.00004255845,0.002589409],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001624494,"threshold_uncertainty_score":0.005434453,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01654739946651534,"score_gpt":0.2417474813961368,"score_spread":0.2252000819296215,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}