{"id":"W3034732466","doi":"10.1371/journal.pgen.1008848","title":"Elevated exopolysaccharide levels in Pseudomonas aeruginosa flagellar mutants have implications for biofilm growth and chronic infections","year":2020,"lang":"en","type":"article","venue":"PLoS Genetics","topic":"Bacterial biofilms and quorum sensing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":90,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"National Institute of Allergy and Infectious Diseases; Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; National Institutes of Health; Children’s Hospital of Wisconsin Research Institute; National Institute of Diabetes and Digestive and Kidney Diseases; Seattle Children's Research Institute; University of Calgary; University of Washington","keywords":"Biology; Mutant; Flagellum; Transposon mutagenesis; Pseudomonas aeruginosa; Mutagenesis; Phenotype; Biofilm; Microbiology; Motility; Mutation; Genetics; Genetic screen; Gene; Virulence; Transposable element; Bacteria; Cell biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001517147,0.0004519534,0.0002755136,0.0003301046,0.0001814248,0.0004903257,0.0002169096,0.000580827,0.001152692],"category_scores_gemma":[0.0002709572,0.00015196,0.0002724716,0.0002343502,0.0003175621,0.0002233902,0.0005753178,0.0006733195,0.0002494208],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002333718,"about_ca_system_score_gemma":0.0002071593,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006908947,"about_ca_topic_score_gemma":0.0006475538,"domain_scores_codex":[0.9998162,0.000030397,0.00002594977,0.00003290786,0.00005500428,0.00003958671],"domain_scores_gemma":[0.9996688,0.0000547651,0.0001261828,0.00002784339,0.00002405319,0.00009827493],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005195546,0.00001663501,0.0005303767,0.00001193687,0.000003294476,0.00009868133,0.00001393725,0.00002189595,0.9988306,0.00003817338,0.00001872219,0.0003636783],"study_design_scores_gemma":[0.00004250377,0.000343811,0.0956421,0.00002768571,0.00005131884,0.002351318,0.0002571616,0.002325399,0.8966989,0.00048588,0.001734744,0.00003915407],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9962807,0.0005226797,0.002131807,0.000207083,0.00002374729,0.000009976054,0.000364608,0.00005772478,0.0004015236],"genre_scores_gemma":[0.9975327,0.0002729206,0.001162391,0.00005663381,0.000006858526,0.0000135049,0.0002206303,0.00002756586,0.00070676],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001152692,"threshold_uncertainty_score":0.003856122,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03137101999103378,"score_gpt":0.2590633538179032,"score_spread":0.2276923338268695,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}