{"id":"W3034732466","doi":"10.1371/journal.pgen.1008848","title":"Elevated exopolysaccharide levels in Pseudomonas aeruginosa flagellar mutants have implications for biofilm growth and chronic infections","year":2020,"lang":"en","type":"article","venue":"PLoS Genetics","topic":"Bacterial biofilms and quorum sensing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":90,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"National Institute of Allergy and Infectious Diseases; Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; National Institutes of Health; Children’s Hospital of Wisconsin Research Institute; National Institute of Diabetes and Digestive and Kidney Diseases; Seattle Children's Research Institute; University of Calgary; University of Washington","keywords":"Biology; Mutant; Flagellum; Transposon mutagenesis; Pseudomonas aeruginosa; Mutagenesis; Phenotype; Biofilm; Microbiology; Motility; Mutation; Genetics; Genetic screen; Gene; Virulence; Transposable element; Bacteria; Cell biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00004850556,0.0001877819,0.0001830613,0.00004742652,0.0001163025,0.00004445426,0.0001114544,0.0001931901,0.000007385578],"category_scores_gemma":[0.0001156613,0.0002016277,0.00005822524,0.0001388869,0.00007589018,0.00000490899,0.0001046487,0.00009080233,0.00000337315],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001768681,"about_ca_system_score_gemma":0.0001051326,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000008462152,"about_ca_topic_score_gemma":0.00008482272,"domain_scores_codex":[0.9988998,0.00003384347,0.00026748,0.0004264973,0.00005576279,0.0003166446],"domain_scores_gemma":[0.9994532,0.00002255109,0.000079185,0.0002166124,0.00008499415,0.0001434913],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002059203,0.00005043615,0.005071536,0.00004228241,0.00004152093,8.963322e-7,0.0000563086,0.00001660224,0.9941137,0.00006079195,0.00008757612,0.0004377544],"study_design_scores_gemma":[0.0006886206,0.0003776544,0.005388399,0.00001396217,0.00004242501,0.00001071822,0.00002554468,0.0008920578,0.9909956,0.00006589438,0.001252395,0.000246716],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9965506,0.0006639821,0.0005505859,0.001372095,0.00006746151,0.0004662643,0.0002430586,0.00002393028,0.00006208292],"genre_scores_gemma":[0.9971144,0.0005502044,0.001351979,0.0004209813,0.0003520284,0.0000321995,0.0001285509,0.00003632362,0.00001336634],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00311809,"threshold_uncertainty_score":0.822214,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03137101999103378,"score_gpt":0.2590633538179032,"score_spread":0.2276923338268695,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}