{"id":"W3034767506","doi":"10.3390/cells9061454","title":"Parkin Overexpression Attenuates Sepsis-Induced Muscle Wasting","year":2020,"lang":"en","type":"article","venue":"Cells","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":52,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; McGill University Health Centre; Institut Universitaire de Gériatrie de Montréal; Université du Québec à Montréal","funders":"Fonds de Recherche du Québec - Santé; Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Parkin; Atrophy; Muscle atrophy; Sepsis; Mitophagy; Mitochondrion; Autophagy; PINK1; Endocrinology; Internal medicine; Biology; Medicine; Cell biology; Apoptosis; Parkinson's disease; Biochemistry; Disease","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002392829,0.0004511093,0.0005304163,0.0002604339,0.0001563816,0.0003094781,0.000201236,0.0003203181,0.0008290767],"category_scores_gemma":[0.000197781,0.0001680681,0.0002288163,0.0001578895,0.0003734259,0.0002637855,0.0002502748,0.0007119174,0.000212406],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002144505,"about_ca_system_score_gemma":0.0002961027,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003253955,"about_ca_topic_score_gemma":0.000548906,"domain_scores_codex":[0.9998319,0.00003536079,0.00002455435,0.0000297945,0.00003017044,0.00004813505],"domain_scores_gemma":[0.9997745,0.00002569264,0.00008633384,0.00001773622,0.00001827348,0.00007755236],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006967164,0.0001461004,0.0001365728,0.0000793296,0.000007085488,0.00006391034,0.00002129655,0.0001155468,0.9967914,0.0000743653,0.00006438985,0.001803271],"study_design_scores_gemma":[0.0001862048,0.00373749,0.004919601,0.00003436634,0.00003925477,0.0002706785,0.00008117551,0.001849319,0.9865245,0.00009800576,0.002249664,0.000009783257],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9963755,0.001305218,0.001241956,0.0001526503,0.00004459526,0.00002969297,0.000205672,0.00009619495,0.0005485617],"genre_scores_gemma":[0.9952257,0.001246304,0.001329585,0.00007467918,0.00001606689,0.00005773683,0.0003458011,0.0000254031,0.001678779],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008290767,"threshold_uncertainty_score":0.002773523,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03874390186540658,"score_gpt":0.2780963470012989,"score_spread":0.2393524451358923,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}