{"id":"W3034767506","doi":"10.3390/cells9061454","title":"Parkin Overexpression Attenuates Sepsis-Induced Muscle Wasting","year":2020,"lang":"en","type":"article","venue":"Cells","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":52,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; McGill University Health Centre; Institut Universitaire de Gériatrie de Montréal; Université du Québec à Montréal","funders":"Fonds de Recherche du Québec - Santé; Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Parkin; Atrophy; Muscle atrophy; Sepsis; Mitophagy; Mitochondrion; Autophagy; PINK1; Endocrinology; Internal medicine; Biology; Medicine; Cell biology; Apoptosis; Parkinson's disease; Biochemistry; Disease","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00004045382,0.0001054917,0.0001649883,0.00001752125,0.00005437584,0.00001197952,0.00006781545,0.00005927386,0.0007641265],"category_scores_gemma":[0.0000360514,0.00008646371,0.00008100689,0.00009659731,0.00001560947,0.00004560951,0.00003618021,0.000123714,0.0004029688],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001349124,"about_ca_system_score_gemma":0.00003440343,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00000394805,"about_ca_topic_score_gemma":5.666607e-8,"domain_scores_codex":[0.9993002,0.00002301313,0.0001377348,0.000208627,0.000153482,0.0001769079],"domain_scores_gemma":[0.9994962,0.000042599,0.00004904571,0.0001666957,0.00002589043,0.0002195941],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004644988,0.00005315797,0.0008715551,0.0000673034,0.00002757001,0.00005354018,0.0004353114,0.000005897328,0.985085,0.000009831533,0.006217337,0.007127105],"study_design_scores_gemma":[0.001053495,0.0001227152,0.008412859,0.0001901979,0.00004778616,0.00000163172,0.0001296287,0.001304517,0.9757568,0.00005236842,0.0128077,0.0001203132],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9932742,0.0003399539,0.00004732683,0.001511473,0.00009625001,0.0001639607,0.000004904353,0.0001135043,0.00444841],"genre_scores_gemma":[0.9949643,0.0000317665,0.0002252662,0.004074892,0.0003938824,0.000006317244,0.00001303109,0.00002267088,0.0002678536],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.009328157,"threshold_uncertainty_score":0.8366649,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03874390186540658,"score_gpt":0.2780963470012989,"score_spread":0.2393524451358923,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}