{"id":"W3034782118","doi":"10.1016/j.semcancer.2020.06.003","title":"The unique immune microenvironment of liver metastases: Challenges and opportunities","year":2020,"lang":"en","type":"review","venue":"Seminars in Cancer Biology","topic":"Cancer Immunotherapy and Biomarkers","field":"Medicine","cited_by":65,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University; McGill University Health Centre","funders":"Canadian Institutes of Health Research; Mitacs; Cancer Research UK; National Institute for Health and Care Research; Ministère de l'Économie, de la Science et de l'Innovation - Québec","keywords":"Immune system; Tumor microenvironment; Context (archaeology); Immunology; Liver cancer; Acquired immune system; Medicine; Colorectal cancer; Cancer; Gastrointestinal cancer; Cancer research; Metastasis; Biology; Hepatocellular carcinoma; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00116505,0.0007268715,0.001613055,0.001335159,0.0002532725,0.001890104,0.0008838565,0.001639566,0.002665804],"category_scores_gemma":[0.001174249,0.0002158078,0.0004224128,0.001358588,0.0009104698,0.002233786,0.001068556,0.002962463,0.001376028],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007589922,"about_ca_system_score_gemma":0.001418683,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007184168,"about_ca_topic_score_gemma":0.001932265,"domain_scores_codex":[0.9997815,0.00005267925,0.00002083078,0.00003341829,0.00008111554,0.00003039],"domain_scores_gemma":[0.9993099,0.00040102,0.00006069177,0.00001556764,0.0001378136,0.00007499359],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00009009273,0.00005071594,0.0002365361,0.008172115,0.00004781787,0.000239881,0.00005426966,0.000338388,0.001863656,0.007294175,0.04882195,0.9327903],"study_design_scores_gemma":[0.00002747945,0.00009758527,0.0007483076,0.003599305,0.00007814561,0.001386176,0.0001166749,0.0001804028,0.0004287901,0.006065515,0.9872468,0.00002488762],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00005086908,0.9983535,0.0001106632,0.000847662,0.0002870133,0.000001315899,0.000006947878,0.000004365446,0.0003377764],"genre_scores_gemma":[0.0006208618,0.9973854,0.0001737658,0.0006431293,0.0008399271,0.000004229513,0.00001526926,0.000001272818,0.0003160046],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002665804,"threshold_uncertainty_score":0.008918047,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1051626951825617,"score_gpt":0.3534766397183523,"score_spread":0.2483139445357906,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}