{"id":"W3034878136","doi":"10.1128/jb.00232-20","title":"Transient Intestinal Colonization by a Live-Attenuated Oral Cholera Vaccine Induces Protective Immune Responses in Streptomycin-Treated Mice","year":2020,"lang":"en","type":"article","venue":"Journal of Bacteriology","topic":"Vibrio bacteria research studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Common Fund; National Institute of Allergy and Infectious Diseases; Natural Sciences and Engineering Research Council of Canada; Government of Canada; Howard Hughes Medical Institute","keywords":"Cholera; Cholera vaccine; Immunogenicity; Vibrio cholerae; Biology; Immune system; Antibiotics; Colonization; Cholera toxin; Vaccination; Immunology; Microbiology; Bacteria","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00041989,0.0006290498,0.0004445725,0.0006197696,0.0002127443,0.000431511,0.0003586419,0.0007237979,0.001823525],"category_scores_gemma":[0.0002711595,0.0003501656,0.0005187248,0.0001934347,0.0005557837,0.0004117774,0.0002449102,0.002351314,0.0007081878],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003456846,"about_ca_system_score_gemma":0.000337602,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004189668,"about_ca_topic_score_gemma":0.0006783275,"domain_scores_codex":[0.9995888,0.00005762775,0.00003784243,0.0001050577,0.00006244441,0.0001482275],"domain_scores_gemma":[0.9995037,0.00008016155,0.0001253563,0.00006702443,0.00004500169,0.0001787349],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004416817,0.0003239257,0.0001972822,0.00003478988,0.000006030913,0.00003603708,0.00005287484,0.00006204617,0.9976947,0.00009379428,0.00006312737,0.0009936021],"study_design_scores_gemma":[0.0001270465,0.006944253,0.005527884,0.00002754016,0.00003001316,0.0002081208,0.0001120189,0.001032731,0.9843737,0.0001056222,0.001499482,0.00001155139],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9935719,0.0005449658,0.002568168,0.0001892757,0.0000980786,0.0001087678,0.0005671082,0.0002059977,0.002145688],"genre_scores_gemma":[0.9877297,0.0005648197,0.002858819,0.0002999292,0.00005119794,0.0001994584,0.0009449087,0.00008676342,0.007264429],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001823525,"threshold_uncertainty_score":0.006100237,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01765833920417292,"score_gpt":0.278623347158972,"score_spread":0.260965007954799,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}